Understanding the role of circadian rhythms in carcinogenesis and tumor progression will enable us to better understand causes of cancer and how to treat ... Monica N. Morgan,S Dvuchbabny,CA Martinez,... - 《Clocks & Sleep》 被引量: 0发表: 2019年 Sirtuins, melatonin and circadian rhythms...
During adolescence, major changes take place in NREM sleep slow-wave activity (SWA), a marker of the homeostatic regulation of sleep and its relationship to circadian rhythms. The exponential decrease of SWA during adolescence seems to parallel cortical maturation and may reflect changes in synapse ...
sleep, a normal, reversible, recurrent state of reduced responsiveness to external stimulation that is accompanied by complex and predictable changes in physiology. These changes include coordinated, spontaneous, and internally generated brain activity as well as fluctuations in hormone levels and relaxation...
Blood pressure and composition of the blood plasma are regulated by hypothalamic mechanisms. The expression of emotions such as fear, rage, and anger are partly controlled by the hypothalamus, and it even helps regulate sleep and levels of consciousness. Location/Anatomy The hypothalamus is a ...
In humans, Thymanax has positive phase shifting properties; it induces a phase advance of sleep, body temperature decline and melatonin onset. Clinical efficacy and safety The efficacy and safety of Thymanax in major depressive episodes have been studied in a clinical programme including 5,...
The most obvious of these circadian rhythms are sleep and wakefulness, which are driven by physiological responses to light and dark; the internal body clock also controls alertness, hunger, digestion, urine production, body temperature, and the secretion of hormones. When these rhythms have been ...
subsequently identified a gene calleddoubletime, which encodes a protein that helps control the frequency of PER protein oscillations in the cell nucleus on a 24-hour cycle. Young’s later research included the investigation of molecular changes in circadian rhythm that underlie sleep disorders in ...