Areas covered: The SERM, clomiphene citrate, which is approved by the FDA for the treatment of ovarian dysfunction, has been shown to have beneficial effects on male hypogonadism. Clomiphene citrate exists as a mixture of both the cis-isomer (zuclomiphene) and the trans-isomer (enclomiphene)....
Enclomiphene citrate is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实验室的科学研究者提供高品质的产品与技术服务,不断促进生命科学领域的新技术发展。
In 2015 the drug manufacturer received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) for its New Drug Application for enclomiphene, which informed them that the application for the drug could not be approved in its present form. Enclomiphene is available under the...