Infections by encapsulated bacteria are important causes of infant mortality worldwide. Over the last 20 years protein-polysaccharide conjugate vaccines have been developed to protect against the major invasive bacterial diseases of childhood, Streptococcus pneumoniae, Haemophilus influenzae type b (Hib) ...
Vaccines for the prevention of encapsulated bacterial diseases: current status, problems and prospects for the futurePrevention of life-threatening infections due to encapsulated bacteria in children with hyposplenia or asplenia: a brief review of c...Phagocytosis as a surface phenomenon. II. Contact...
Infections by encapsulated bacteria are important causes of infant mortality worldwide. Over the last 20 years protein-polysaccharide conjugate vaccines have been developed to protect against the major invasive bacterial diseases of childhood, Streptococcus pneumoniae, Haemophilus influenzae type b (Hib) and...
Such conjugated vaccines have been shown to be effective against the most common causes of invasive disease caused by encapsulated bacteria in neonates and children. These and several other approaches in current vaccine development will be discussed. ...
In vaccine development, especially against pathogenic encapsulated extracellular bacteria, functional assays such as the opsonophagocytosis assay (OPA) are preferred to ELISA titers for evaluating protection against infection. Such assays are normally performed using phagocytic cell lines or purified cell ...
Thus, mRNA-LNP can be used to rapidly generate single or multi-component vaccines, such as sequential vaccines needed to protect against HIV-1 infection. Such vaccines would be as or more immunogenic than adjuvanted recombinant protein vaccines in primates. 展开 ...
Enhancing in situ cancer vaccines using delivery technologies Ningqiang Gong Mohamad-Gabriel Alameh Michael J. Mitchell Nature Reviews Drug Discovery (2024) Long-term relapse-free survival enabled by integrating targeted antibacteria in antitumor treatment Yuanlin Wang Yaqian Han Miao Yu Nature Comm...
Encapsulation of vaccines in biodegradable microspheres provides excellent mucosal immunogens with a high potential for immunization against bacterial infe... K Allaouiattarki,S Pecquet,E Fattal,... - 《Infection & Immunity》 被引量: 133发表: 1997年 Enhanced immune response to T-independent antigen...
bacteriacellfromthedestructionbyleukocytes(NauandEiffert, 2002).Thecapsularpolysaccharidesareusedfortheserologicclassifica- tionofstrains,and91serotypesarecurrentlyrecognised(Parketal., 2007). There are several conjugate vaccines that offer protection against a limited number of pneumococci depending on the ...
However, it is possible that the gut microbiome is enriched by anaerobic bacteria that release more enzymes to degrade plant cell wall than protein degradation. Bacteria inhabiting the human gut have indeed evolved to utilize complex carbohydrates in plant cell wall and are capable of utilizing ...