Enantiomeric Excess Formula To get a sense of how this equation works, let's look at the easy examples first. If there is a solution with 0.4 M of the R-enantiomer and 0.4 M of the L-enantiomer, there is an enantiomeric excess of: {eq}ee% = 100*\frac{0.4-0.4}{0.4+0.4} {/...
The invention provides a method for the preparation of enantiomerically pure mirtazapine, said method comprising a step of ring closure of a compound of formula (II) wherein X is a leaving group, said step comprising treatment with an acid, whereby mirlazapine with enantiomeric excess is formed...
Novel compounds in enantiomeric excess that are inhibitors of bacterial methionyl synthetase (MetRS) are disclosed. Also disclosed are methods for their preparation and their use in
The invention concerns a process for the preparation of an alpha -substituted- alpha -cyanomethyl alcohol enantiomer of formula I wherein the group R<1> is an alkenyl, alkynyl, aryl or heteroaryl group by reacting an aldehyde of ... WILLIAM ROY JACKSON,BARRY ROSS MATTHEWS,COLIN WILSHIRE - ...
and enantioselectively reducing an imine with a reducing agent/chiral auxiliary agent complex so as to produce an enantiomeric excess of R enantiomer of the compound of formula (I) over the S enantiomer of the compound of formula (I... BC Vanwagenen,RM Barmore - CA 被引量: 29发表: 1997...
To solve the problem, we need to determine the percentage of the enantiomer that is present in lower concentration in a mixture of two enantiomers of compound P. The specific optical rotations of the enantiomers are given as +100° and -100°, and the
Novel bicyclic amides of the formula wherein Ar<1> and Ar<2> are phenyl, R<2>-substituted phenyl, heteroaryl or R<2>-substituted heteroaryl, wherein R<2> is 1 to 3 substituents independently selected from the group consisting of h... JW Clader,T Fevig,W Vaccaro,... - WO 被引量...
10. The process of claim 1 wherein the β-lactam has the formula: wherein X1is —OX6; X2is hydrogen, hydrocarbyl, substituted hydrocarbyl, or heterocyclo; X3is hydrogen, hydrocarbyl, substituted hydrocarbyl, or heterocyclo; X4is hydrocarbyl, substituted hydrocarbyl, or heterocyclo; X5...
Enantiomeric separa2 tion of substituted aryloxy propionic esters / Application to t he determination of t he enantiomeric excess in herbicide formula2 tions[J ] . J . Chromatogr. , 1991 , 541 :3492 357.Tambute A,Siret L,Caude M,Rosset R.Enantiomeric separation of substituted aryloxy ...
Enantiomeric enrichment of an enantiomeric mixture of alpha -amino acids (I) to produce an enantiomeric excess of at least 65% involves cold precipitation of the racemate from a solvent and separation of the pure enantiomer from the remaining solution. Enantiomeric enrichment of an enantiomeric ...