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Statistical analysis of data from both groups showed a significant difference for the analyte enalapril, but not for enalaprilat. Moreover, NCX899 and enalapril were equally effective in inhibiting the activity of serum angiotensin-converting enzyme.4. In anaesthetized dogs, i.v. administration of ...
The adverse effects of enalapril are the same as for allACE inhibitors, as outlined above. Chronic high-dose enalapril toxicity appears to be confined to the kidneys. In healthy dogs administered doses up to 15 mg/kg/d over 1 year, drug-inducedrenal lesionsare not seen. High-dose (30–...
The dogs were randomized to enalapril (EN) therapy (2 mg/kg/day, n=10) or to a control group (n=10). Echocardiography was performed at baseline and weekly thereafter. At the 5-week electrophysiological study, AF was induced by burst pacing and AF duration was measured. Results: Atrial ...
It is being explored as adjunctive treatment in chronic renal failure and protein losing nephropathies. While ACE inhibitors are a mainstay for treating hypertension in humans, they have not been particularly useful in treating hypertension in dogs or cats. View all ...
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of angiotensin I, II, III, IV, 1‐5, and 1‐7, and aldosterone, and urinary aldosterone‐to‐creatinine ratio (UACR) from pCKD dogs were compared to values on day 30 of treatment with enalapril (0.5 mg/kg PO q12) or telmisartan (1 mg/kg PO q24h) and to those of hea...
PDA was diagnosed by using Doppler, echocardiography, electrocardiography, X-ray, and blood analysis in 5 golden retrievers. Carprofen (2 mg/kg) and enalapril (0.5 mg/kg) were administered daily for 12 months and the dogs were controlled at 3monthly intervals. Ductal construction was detected ...