The combination of enalapril and HCTZ reduces blood pressure better than either drug alone. The FDA approved Vaseretic in October 1986. What brand names are available for enalapril and hydrochlorothiazide? Vaseretic Is enalapril and hydrochlorothiazide available as a generic drug? Yes Do I need a...
Enalapril is an antihypertensive drug of the class of angiotensin-converting enzyme inhibitors (ACEI) used in pregnancy for treatment of pre-existing or pregnancy-induced hypertension. The use of ACE inhibitors (drugs that act directly on the renin-angiotensin system) during the second...
Renal function and antihypertensive drug efficacy were determined in a prospective, double-blind, multicenter study comparing enalapril plus hydrochlorothi... SS Franklin,RD Smith - 《American Journal of Medicine》 被引量: 369发表: 1985年 Enalapril in treatment of hypertension with renal artery stenos...
This drug belongs to the class of medications called angiotensin-converting enzyme inhibitors. It can be found under the brand name of Lotensin. It works by relaxing the blood vessels. This reduces the amount of work the heart has to do to pump blood, ultimately, lowering the blood pressure....
Package insert / product label Generic name: enalapril maleate Dosage form: oral solution Drug class: Angiotensin Converting Enzyme InhibitorsMedically reviewed by Drugs.com. Last updated on Oct 6, 2024.On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindicat...
The primary route of elimination is renal: the respective renal clearances of enalapril and enalaprilat are about 18 L/h and 9 L/h. Enalaprilat has polyphasic elimination kinetics, with drug persistence during the terminal phase representing the strong binding of enalaprilat to serum ACE. The ...
Pharmacologic class: Angiotensin-converting enzyme (ACE) inhibitor Therapeutic class: Antihypertensive Pregnancy risk category C (first trimester), D (second and third trimesters) FDA Box Warning • When used during second or third trimester of pregnancy, drug can cause fetal injury and even death...
tubular cells, but not the basement membrane, is present. Dogs that survive the initial insult to the proximal tubules undergo regeneration. A dose of 90–200 mg/kg/d is rapidly lethal through renal failure. The renal toxicity appears to be due to a direct nephrotoxic effect of the drug ...
in 60 patients to evaluate the effects of this drug on these parameters.Results: There was a significant inverse relationship between maximal work load and the HR X WR slope, and also between the fractional shortening and the slope, suggesting that the slope may reflect the severity of cardiac...
- 《Drug Metabolism & Disposition the Biological Fate of Chemicals》 被引量: 133发表: 1988年 Age and the pharmacokinetics and pharmacodynamics of chronic enalapril treatment. Enalapril clearance after single doses is reduced in the elderly. The influence of age on the pharmacokinetics and ...