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The pharmacodynamics of enalapril have been examined in experimental dogs. A dose of 0.3 mg/kg administered per os results in approximately 75% inhibition of the pressor response to angiotensin I. This effect lasts for at least 6 h and is completely dissipated by 24 h after administration. A ...
, and ejection fraction), as determined by serial two-dimensional echocardiography, hemodynamics, postmortem topography (planimetered short- and long-axis ventricular contours), and collagen content (determined by levels of hydroxyproline, a marker for collagen), was measured in 25 instrumented dogs....
41: 319-25. PMID: 24127029 Decreased sympathetic tone after short-term treatment with enalapril in dogs with mild chronic mitral valve disease. | Chompoosan, C., et al. 2014. Res Vet Sci. 96: 347-54. PMID: 24559801 Simultaneous quantitative and qualitative analysis of aliskiren, enalapril ...
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Hemodynamic effects of Enalapril and B‐type natriuretic peptide on the progression of pacing induced cardiac myopathy in conscious dogs Enalapril and B‐type natriuretic peptide (BNP) are used in cardiovascular clinical practice as a common anti‐hypertensive drugs and a diagnostic marker of heart fai...
DuP 753 is a specific antagonist for the angiotensin receptor Hypertension, 17 (1991), pp. 480-484 View in ScopusGoogle Scholar 8 P Wong, S Hart, J Duncia, P Timmermans Nonpeptide angiotensin II receptor antagonists: studies with DUP 753 and EXP3174 in dogs Eur J Pharmacol, 202 (1991)...
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Echocardiographic LVmass (LVM) was from the cubic function: LVM (mg) = 1.04[(EDD + PWT + IVS)3 – EDD3], corrected for body weight (LVMI), since echocardiography permits better identification of differing patterns of hypertrophy. Terminal hemodynamics were volumetric aortic flow (mean: MAF, ...