Edited by: Inti Zlobec, University of Bern, Switzerland Reviewed by: Parham Minoo, University of Calgary, Canada Qianghua Xia, The Children’s Hospital of Philadelphia, USA *Correspondence: Eva Karamitopoulou, Clinical Pathology Division, Institute of Pathology, University of Bern, Murtenstrasse 31...
of PDAC. Recent evidence suggests that epithelial-mesenchymal Qianghua Xia, The Children’s Hospital transition (EMT) plays an important role to the disease progression and development of of Philadelphia, USA drug resistance in PDAC. Tumor budding is thought to reflect the process of EMT which ...
ofPhiladelphia,USA *Correspondence: EvaKaramitopoulou,Clinical PathologyDivision,Instituteof Pathology,UniversityofBern, Murtenstrasse31,CH-3010Bern, Switzerland e-mail:eva.diamantis@ pathology.unibe.ch Pancreaticductaladenocarcinoma(PDAC)ranksasthefourthcommonestcauseofcancer deathwhileitsincidenceisincreasingworl...
and that 3% of the total population live with a serious psychiatric disorder at any one point in time.1 Fundamental changes to health-care policy in Australia and around the world have led to an increase in the extent to which emergency personnel come into contact...
snail与emt相关蛋白在转移性脊柱肿瘤中的表达word论文.docx,性脊柱肿瘤中的表达明显高于正常组织,差异有显著意义(X2=7.94, P0.05)。根据Tomita得分,转移性脊柱肿瘤患者中A+B组(36例)与C+D(24 例)组之间Snail的阳性表达分别为24例(66.67%)、23例(95.83%),两组
M. et al. Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 99, 319–325 (2002). CAS PubMed Google Scholar Kottke, T. et al. Broad antigenic coverage induced by vaccination with virus-based cDNA ...
It is clear that the well-described phenomenon of epithelial–mesenchymal transition (EMT) plays a pivotal role in embryonic development, wound healing, tissue regeneration, organ fibrosis and cancer progression. EMTs have been classified into three subtypes based on the functional consequences and biom...
The role of Zeb1 in metastatic dissemination has been thoroughly studied; leading to additional findings of its role in subverting cell cycle exit programs: senescence and apoptosis. Partial down-regulation of Zeb1 is sufficient to induce senescence in mouse xenograft models49. Mutations in Zeb1 have...
Snail与EMT相关蛋白在转移性脊柱肿瘤中的表达.pdf,60 例转移性脊柱肿瘤中,51 例染色呈阳性表达(85.00%);20 例正常组 中9 例染色呈阳性表达(35.00%)。转移性脊柱肿瘤与正常组比较:Vimentin 2 在转移性脊柱肿瘤中的表达明显高于正常组织,差异有显著意义(X =18.81, P
Cancer: Principles & Practice of Oncology: Primer of the Molecular Biology of Cancer; Wolters Kluwer Health/Lippincott Williams & Wilkins: Philadelphia, PA, USA, 2011. [Google Scholar] Van Dam, P.-J.; Van Laere, S. Molecular profiling in cancer research and personalized medicine. In Oxford ...