Then, we selected prognosis-associated gene pairs, which were significantly correlated with disease-free survival of stage II CRC using multivariate Cox regression model, as the EMT-related prognosis signature. Results An EMT-related signature composed of fifty-one gene pairs (51-GPS) for prediction...
5-Fluorouracil (5-FU) is a pyrimidine analog chemotherapeutic drug currently being used in clinical practice since the 1950s as a first-line treatment option for CRC6,7. Although the drug efficiently reduces primary tumor mass initially, cases of recurrence have been reported frequently indicating ...
Recent advances in the high-volume comprehensive genomic sequencing of human tumor samples can help link the PC underlying mechanisms with clinical practice. Analyses using algorithms on comprehensive transcriptomes enable a deeper understanding of the clinical relevance of various signaling pathways and ...
3.3. Effects of Spatial Distribution of LOXL2 To get some idea of what might happen in practice for a localized tumor, we imagine that cells in some spherical region of radius R form a tumor of a constant cell density ρ and are emitting LOXL2 at a constant rate α. These molecules ...
molecules Article β-Asarone Inhibits Invasion and EMT in Human Glioma U251 Cells by Suppressing Splicing Factor HnRNP A2/B1 Li Li, Mingxia Wu, Chengqiang Wang, Zanyang Yu, Hongmei Wang, Hongyi Qi * ID and Xiaoyu Xu * College of Pharmaceutical Sciences, Southwest University, Chongqing 400716...