几项研究表明,可逆的上皮向间充质转化(EMT)促进转移:癌细胞首先从上皮转化为间充质样细胞状态(EMT),使它们能够离开原发肿瘤并迁移到远处。当它们定植于远处器官时,通过间充质到上皮的转变(MET)采用上皮样状态允许转移瘤的生长。所需的癌细胞可塑性,允许在亚稳...
The Email Mining Toolkit (EMT) is an offline data analysis system designed to assist a security analyst compute, visualize and test models of email behavior for use in MET. In this paper, we enumerate the features implemented in the EMT system.Stolfo, S.J....
Epithelial mesenchymal transition (EMT) is a process of conversion of polarised epithelial cells into mesenchymal cells. First discovered in embryonic development, EMT and a reverse process of mesenchymal epithelial transition (MET) were later implicated in human diseases, organ fibrosis, and cancer. EM...
As our understanding of Epithelial Mesenchymal Transition (EMT) increases, the original binary concept of E versus M no longer fits with experimental evidence. Re-definition of the EMT paradigm as spectral transitions between a full epithelium and a full
《EMT-MET双向调控在人特发性肺间质纤维化发病中的作用》是依托中国人民解放军第四军医大学,由赵峰担任项目负责人的面上项目。中文摘要 特发性肺纤维化(IPF)是一种发病率高、发病机制不明、临床治疗效果差的疾病。目前,绝大多数关于IPF的研究结果均是以动物模型为基础的,与人体IPF的本质具有很大的差异...
It is found that different pathway in the phase diagram can correspond to the EMT or the MET process of cancer cells, and there are two possible EMT processes. It is important that the experimental phenomenon of E/M hybrid state appearing in the EMT process but rather in the MET process ...
《miR-382调节EMT-MET对肾小管间质纤维化分子病理机制的意义》是依托复旦大学,由方艺担任项目负责人的青年科学基金项目。项目摘要 肾小管间质纤维化是所有慢性肾脏疾病的共同病理特征,而肾小管间质纤维化.的发生与肾小管上皮细胞EMT转化及肾间质细胞MET逆转的实时调节密切关联。微小RNA.(microRNAs,mi...
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In this review we summarize the cellular and molecular events of inflammation induced epithelial-to-mesenchymal (EMT) and mesothelial-to-macrophage transition (MET) during regeneration. Since the receptor transmits the environmental stimulus, downregulating or upregulating the process on an epigenetic ...