The emphysematous changes were evaluated by previously described histological and biochemical parameters and by a new method employing infiltration of the lungs with vinyl acetate to make casts of the air spaces of the pulmonary tree. The weights and gross and microscopic appearance of the casts ...
We did not observe any significant changes in the lung compliance between the saline and elastase groups as we expected to only see a mild emphysema with our treatment. We believe that this might be because of the low dosage that has been administered to the rats (50U per animal). Another...
Technique to reduce air leaks after the resection of emphysematous lung Alveolar wall apoptosis causes lung destruction and emphysematous changes. Bronchial fenestration improves expiratory flow in emphysematous human lungs Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes ...
Dyspnea is probably due to the change in the configuration of the thorax which is secondary to hyperinflation. The investigation should include the radiologic quantification of the structural abnormalities of the lungs and the functional consequences of these changes. When volume reduction of the lung ...
Emphysema-related molecules including protease/antiprotease expression were assessed by qPCR and ELISA.Results: Histological examination revealed premature emphysematous changes in the lungs, in evidence as early as 5 weeks of age. Static compliance and the K value (Salazar-Knowles equation) were higher...
Immunohistochemical studies in control mice demonstrated that collagen fibers in the alveolar walls and ducts of the normal mouse lungs consist mainly of type III collagen. In the transgenic and hybrid mice, the emphysematous changes, which developed, were associated with a marked decrease in type ...
Emphysematous changes frequently occurred throughout the lung, but inflammation and fibrotic lesions were usually confined to focal areas. The severity of this phenotype varied significantly among individual mice within the same SPC-PDGFB transgenic lineage. A pathology similar to that observed in adult...
BACKGROUND: The p53 signaling pathway may be important for the pathogenesis of emphysematous changes in the lungs of smokers. Polymorphism of p53 at codon 72 is known to affect apoptotic effector proteins, and the polymorphism of mouse double minute 2 homolog (MDM2) single nucleotide polymorphism ...
Figure 1. Computer tomography scan showing enlarged bilateral kidneys with emphysematous changes within the renal parenchyma. DIAGNOSIS Acute anuric renal failure owing to bilateral emphysematous pyelonephritis. CLINICAL FOLLOW-UP She was admitted to the surgical intensive care unit, and was started on int...
Emphysema, a progressive, often incurable disease of the lungs often results from chronic infection or irritation of the bronchial tubes. As the bronchial tubes become irritated, some of the airways may be obstructed, trapping air in the alveoli. As this process continues, the alveoli become enlar...