Emphysematous changes frequently occurred throughout the lung, but inflammation and fibrotic lesions were usually confined to focal areas. The severity of this phenotype varied significantly among individual mice within the same SPC-PDGFB transgenic lineage. A pathology similar to that observed in adult...
Further highlighting the possibility of impaired elastogenesis, the postmortem lungs of two SIOD patients showed enlarged air spaces or emphysematous changes, a common feature in disorders of elastogenesis[7, 30, 31]. Given these observations, we hypothesized that osteopontin deficiency and/or impaired...
Scrub typhus is milder, with less severe vascular changes and only rare thrombosis and necrosis. Acute renal failure may occur.77,78 R. rickettsii, the causative agent of Rocky Mountain spotted fever, is transmitted by the bites of ticks. Small mammals are reservoirs. In the early stage...
Emphysematous changes frequently occurred throughout the lung, but inflammation and fibrotic lesions were usually confined to focal areas. The severity of this phenotype varied significantly among individual mice within the same SPC-PDGFB transgenic lineage. A pathology similar to that observed in adult...
The functional and morphological changes that occur in emphysema have largely been attributed to changes in alveolar elastin rather than in collagen. A study was performed to determine whether the amount of collagen in the alveolar wall changes with age in the lungs of non-smokers and of smokers...