Emerging functions of the EGFR in cancerdoi:10.1002/1878-0261.12155Sara SigismundDaniele AvanzatoLetizia LanzettiSigismund S, Avanzato D, Lanzetti L. Emerging functions of the EGFR in cancer. Mol Oncol. 2017; 10: 1878-0261.
Emerging functions of the EGFR in cancer. Mol. Oncol. 12, 3–20 (2018). PubMed Google Scholar Hu, W. et al. Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia. Cell Death Dis. 12, 1...
Emerging functions of the EGFR in cancer Mol. Oncol. (2018), 10.1002/1878-0261.12155 Google Scholar Sokolowska-Wedzina et al., 2017 A. Sokolowska-Wedzina, G. Chodaczek, J. Chudzian, A. Borek, M. Zakrzewska, J. Otlewski High-affinity internalizing human scFv-Fc antibody for targeting ...
The interaction between programmed cell death ligand 1 (PD-L1), which is expressed on the surface of tumor cells, and programmed cell death 1 (PD-1), which is expressed on T cells, impedes the effective activation of tumor antigen-specific T cells, resulting in the evasion of tumor cells ...
Herein, we review the current knowledge regarding circRNA biogenesis, regulation and functions in cancer as well as their clinical potential as biomarkers, therapeutic agents and drug targets. Key points Human cells produce many more unique circular RNAs (circRNAs) than we have protein-coding genes;...
The dual functions of exosomes Exosomes are natural nanocarriers that inherit the molecular characteristics of their donor cells, including proteins, lipids, and nucleic acids, which can significantly influence their therapeutic potential in gene therapy and immunotherapy [32]. This cargo can exert either...
EGFR pathway in cancer and launched EGFR inhibitors EGFR-targeted therapy in the clinic Mechanisms of acquired resistance to third-generation EGFR-TKIs Exploration of next-generation EGFR-TKIs Sequencing technology accelerating the realization of EGFR-targeted precision therapy Conclusions and future perspecti...
In this Review, we describe recent cancer genomic studies that have assembled emerging views of the landscapes of somatic mutations through deep-sequencing analyses of the coding exomes and whole genomes in various cancer types. We discuss the comparative genomics of different cancers, including ...
This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple cancer types. As small extracellular vesicles, exosomes exhibit high
Sammons Cancer Center at Baylor University Medical Center, of the Study 205 findings. “Combination therapy is here to stay for kidney cancer.” With that advancement making an impact in clinical practice, researchers are also exploring the potential the combination could have in the frontline ...