NEB 中国 2020 年 7 月,英国爱丁堡大学 Dónal O’Carroll 研究团队在 Nature 杂志上发表题为 SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation 的文章,借助多项测序技术,鉴定得到了新型的 MIWI2 相互作用因子 SPOCD1,并且发现该因子对于 piRNA 指导的转座元件甲基化过程非常关键。 在...
To overcome the drawbacks of bisulfite sequencing, we developed an enzyme based methylation detection technology, called NEBNext Enzymatic Methyl-Seq (EM-Seq), that minimizes damage to DNA enabling longer insert sizes, lower duplication rates and minimal GC bias resulting in more accurate ...