capture assay is called a “sandwich” assay because the analyte to be measured is bound between two primary antibodies, each detecting a different epitope of the antigen–the capture antibody and the detection antibody. The sandwich ELISA format is hi...
Designed to suit a wide variety of needs, the Varioskan LUX Multimode Microplate Reader has a flexible range of measurement modes. The instrument simplifies measurement setup with automatic dynamic range selection, and its smart safety controls help you avoid experimental errors. It features five dete...
The sandwich ELISA format is highly used because of its sensitivity and specificity. Diagram of common ELISA formats (direct vs. sandwich assays). In the assay, the antigen of interest is immobilized by direct adsorption to the assay plate or by fi...
mechanism. Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions. IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha. IL-1 beta activity can...
Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties. humancell culture supernatants Oxid Med Cell Longev Tilianin Ameliorates Cognitive Dysfunction and Neuronal Damage in Rats with Vascular Dementia vi...
regulates proliferation, differentiation, adhesion, migration in many cell types. Many cells have TGF beta receptors, and the protein positively and negatively regulates many other growth factors. TGF beta-1 is cleaved into a latency-associated peptide and a mature TGF beta-1 peptide, and is ...
Advantages of ELISA include its high sensitivity, ease of use, and compatibility with automation. In addition, ELISA allows for testing a broad range of sample types, including cell lysates, culture supernatants, and tissue extracts, as well as bodily fluids such as serum, urine, and saliva. ...
1997. The complex between urokinase plasminogen activator and its type-1 inhibitor in breast cancer extracts quantitated by ELISA. J Immunol. Methods 203 : 55–65.Pedersen, AN, Hoyer-Hansen, G, Brunner, N, Clark, GM, Larsen, B, Poulsen, HS, Dano, K, Stephens, RW (1997) The complex ...
and MCP-1 on a variety of cell types. IL-17A is also involved in the activation of NF-kB and costimulation of T cell proliferation. As a result of these roles, IL-17A has been linked to many immune/autoimmune related diseases including rheumatoid arthritis, asthma, lupus, and multiple scl...
It contributes to the development of type 2 diabetes through its effects on insulin resistance and fatty acid metabolism. Long Name: Tumor Necrosis Factor alpha Entrez Gene IDs: 7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 102139631 (...