In a survey of 32 consecutive outpatients with anorexia nervosa and/or bulimia nervosa, about 9% of patients had elevated serum uric acid levels at the time of their initial assessment. These patients had a history of regular strenuous exercising and prolonged or periodic starvation, in the ...
All these events contribute to the increased oxidative stress levels responsible of neurodegeneration observed in AD brain. Although insulin resistance and Aβ production can be considered leading causes of the rise of oxidative stress, this latter, in turn, promotes IRS-1/2 Ser-312, -616 and -...
Because of a selection procedure, all groups were matched for age, BMI, insulin sensitivity and prolactin levels. In addition, there were no proportional differences between the groups for the various causes of prolactin excess. Due to the stringent inclusion and exclusion criteria, the impact of ...