Protein carbonyl levels, a measure of protein oxidation, were found to be significantly elevated (p < 0.0005) in the sera of chronic fatigue syndrome (CFS) patients vs. controls. In contrast, the total protein levels in sera CFS patients were unchanged from those of controls. The elevated ...
Equal amounts of total protein were separated by SDS-PAGE, transferred by Western blot analysis, and detected with anti-StARD3, anti-Src, or anti-actin antibodies (Abs). C: Quantification of StARD3 levels by densitometry. D: Quantification of Src levels by densitometry. Data represent means ...
Elevated temperature negatively affects R protein-mediated disease resistance19,20. Zhu et al. (2010) showed that loss of R protein nuclear localization contributes to compromised R-mediated defence at elevated temperature (28 °C)38. NPR1 is a key regulator of SA signalling and accumulates in ...
et al. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood.1993;82:513-520.Google Scholar 41. Harris TB, Ferrucci L, Tracy RP. et al. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med....
The shelterin protein TRF2 is essential for chromosome-end protection. Depletion of TRF2 causes chromosome end-to-end fusions, initiating genomic instability that can be cancer promoting. Paradoxically, significant increased levels of TRF2 are observed i
To measure the levels of high-sensitivity C-reactive protein and ferritin in blood and to assess their association with inflammation in people with Type 2 diabetes.The case-control study was conducted between November 2012 to November 2013 at the Basic Medical Sciences Institute, Jinnah Postgraduate...
Fibroblast growth factor 21 (FGF21) is a liver-secreted peptide hormone reportedly improving metabolic homeostasis, partly via reduced hunger for sugar, fat, protein and alcohol. Exogenous glucagon has been shown to increase circulating FGF21 levels, but the role of endogenous glucagon for the ...
We investigated the clinical value of serum levels of neuron-specific enolase (NSE) and human soluble protein-100β (S-100β) in acute cerebral infarction (ACI) patients. A literature search of electronic databases identified relevant case-control studies that examined the correlations between NSE ...
The deposition of aggregated amyloid-β peptides derived from the pro-amyloidogenic processing of the amyloid precurson protein (APP) into characteristic amyloid plaques (APs) is distinctive to Alzheimer’s disease (AD). Alternative APP processing via the metalloprotease ADAM10 prevents amyloid-β form...
Conclusion: The increased levels of alkanals, alkenals and 4-HO-alkenals of lipid peroxidation in the plasma of HD patients may greatly contribute to the toxicity of RCOs. The pattern of modification of plasma protein by each group of aldehydes may provide new evidence on the in vivo ...