Interaction signals were also observed within the HLA class I region, within the HLA class II region, and between the HLA class I and class III regions. Fig. 4: MS association in the HLA region. a–g, Comparison of variance explained in MS within the UK Biobank for all fine-mapped HLA...
a, Local ancestry anomaly score measuring the difference between the local ancestry and the genome-wide average (capped at –log10(P) = 20;Methods). Significant peaks (reaching genome-wide significanceP < 5 × 10–8, two-tailedttest before adjustment for multiple testing, as sho...
There was a correlation between log blood Mn and PI ( 蟻 = 0.384, P = 0.048; n = 27) in IDA patients. None of the patients showed increased signals in the globus pallidus in T1-weighted MRI. Blood Mn levels decreased and hemoglobin levels increased after iron therapy ( P < 0.05). ...
We suggest that the elevation of brain apoE in tg2576 mice participates in an age-related dys- regulation of A clearance and signals the start of A sequestration during the time of cognitive dysfunction. Introduction Alzheimer's disease (AD) is characterized by progressive dementia and by...
2003. Hormonally derived sex pheromones in fish: exogenous cues and signals from gonad to brain. Can. J. Physiol. Pharmacol. 81:329–341. CrossRef Zohar, Y., Muñoz-Cueto, J. A., Elizur, A., and Kah, O. 2010. Neuroendocrinology of reproduction in teleost fish. Gen. Comp. ...
a• Like the three LEDs, the buzzer guides you to the target torque (or angle); it increases the frequency of its signals as torque (or angle) increases, and emits a different signal if the torque (or angle) goes over the maximum value. • 象三LEDs,蜂音器引导您到目标扭矩 (或...
e, Genome browser view of CUT&RUN signals for H3K36me2 and H3K27me3 on the indicated genes and conditions. Arrow indicates the direction of gene transcription. f, Loss of occupancy of NSD3(T1242A) and H3K36me2 at the indicated NSD3 target genes (Irgm1 and Prkaa2) upon NSD3 ...
[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis. Glucose-induced insulin release from pancreatic beta cells depends on the beta-cell metabolism of glucose, which generates intracellular signals for secret... Tal,Y J,Wu,... - 《Proceedings of...
erbB-2 (ErbB2) protein is a cell surface transmembrane tyrosine kinase that forms long-lived, potent heterodimers with other receptors of the epidermal growth factor receptor family, and acts as a networking receptor that mediates growth, survival, migration, and proliferation signals to cancer ...
(right) enrichment signal in differential enriched peaks. There are 28,347 and 32,326 enriched H3K9me2 and H3K9me3 peaks in naïve PSCs and 13,701 and 9,832 enriched H3K9me2 and H3K9me3 peaks in primed PSCs, respectively. The ChIP-seq signals are calculated as log2 ratio of ...