Four housekeeping genes, TATA binding protein, ubiquitin C, beta- actin and cyclophilin A, with stable expression, were chosen for normal- ization through calculation of a geometric mean. Probe ID's and M-values (to test for stability of control mRNAs) are provided in Supplementary Methods. ...
Preliminary research suggests that higher than normal levels of the protein albumin in urine is associated with an increased risk for blood clots in the deep veins of the legs or lungs (venous thromboembolism; VTE), according to a study in the May 6 issue ofJAMA. Ad The overall incidence of...
However, the cells that cause ASD through elevated protein synthesis resulting from these mutations remain unknown. Here we employ conditional overexpression of translation initiation factor eIF4E to increase protein synthesis in specific brain cells. We show that exaggerated translation in microglia, but ...
Elevated lead levels were discovered in blood samples collected from family members where both the father and the mother worked in a radiator repair workshop. The father and mother were found to have blood lead levels of 2.0 and 0.5 mumol/L (41.7 and 10.4 micrograms/dL), respectively. The ...
Short-term effects of protein intake, blood pressure, and antihypertensive therapy on glomerular filtration rate in the Modification of Diet in Renal Disease Study. J Am Soc Nephrol. 1996;72097- 2109Google Scholar 34. van de Ven PJBeutler JJKaatee RBeek FJMali WPKoomans HA Angiotensin ...
Blood plasma, Dickkopf‐1, ELISA, Fanconi anemia, infectionsIntroductionDickkopf‐1 (DKK1) is a soluble protein and antagonist of the Wnt/β‐catenin signaling pathway. DKK1 is found elevated in serum from patients affected with various types of cancers and in some instances, it is considered ...
In the assay a pair of oligonucleotide-labeled antibodies (PEA-probes) bind to the target protein in the serum sample. When the two probes are in close proximity, a new PCR target sequence is formed by a proximity-dependent DNA polymerization event. This complex is subsequently detected and ...
Our study has identified 14 significantly elevated vascular transformation biomarkers and developed a simple two-protein profile for Long-COVID status; however, our study has several limitations. First, our study investigated a conservative number of patients within each patient group. Nonetheless, we ...
The deposition of aggregated amyloid-β peptides derived from the pro-amyloidogenic processing of the amyloid precurson protein (APP) into characteristic amyloid plaques (APs) is distinctive to Alzheimer’s disease (AD). Alternative APP processing via the metalloprotease ADAM10 prevents amyloid-β form...
Protein Expr. Purif. 3, 236–245 (1992). Article PubMed CAS Google Scholar Pankhurst, M. W. & McLennan, I. S. Human blood contains both the uncleaved precursor of anti-Mullerian hormone and a complex of the NH2- and COOH-terminal peptides. Am. J. Physiol. Endocrinol. Metab. 305,...