CSF glucose was normal and IgG index was elevated. Autoimmune encephalitis was considered in the differential diagnosis. EEG revealed periodic complexes characteristic of subacute sclerosing panencephalitis (SSPE). Measles vaccination series was incomplete in both patients; one had had clinical measles 20...
Elevated cerebrospinal fluid IgG index in acute cerebellitis presenting with sudden onset headache.Acute cerebellitis is a rare inflammatory syndrome and is one of the important causes of acute cerebellar dysfunction in children. The cerebrospinal fluid (CSF) IgG index is most often tested clinically ...
The deposition of aggregated amyloid-β peptides derived from the pro-amyloidogenic processing of the amyloid precurson protein (APP) into characteristic amyloid plaques (APs) is distinctive to Alzheimer’s disease (AD). Alternative APP processing via th
Additionally, similar clinical features and laboratory findings, including increased cerebrospinal fluid (CSF) interleukin-6 (IL-6) levels, were reported in AQP4-IgG-positive NMOSD (AQP4 + NMOSD) and MOG-IgG-associated disorders (MOGAD)5,6,7. Favorable clinical outcomes were reported in MOG...
accompanied by varying degrees of secondary pain, such as rheumatoid arthritis [22], knee osteoarthritis (OA) [23], tuberculosis infection and disease [36], postmenopausal osteoporosis [78], IgG4-related disease [8], pre-eclampsia [67], squamous cell carcinoma [37], chronic kidney disease [53...
(Fig.2l). GRE1 is in the 5’ UTR, which is most likely a regulatory region. ChIP-qPCR analysis revealed enrichment of GR antibody (compared with IgG) at both GREs in larval brain samples, supporting that GR does indeed bind to regulatory regions of therx3gene (Fig.2m). Further, ...
Mouse IgG1 magnetic bead conjugates (Cell Signaling) were used as experimental control. Glutamate Clearance Assay Transfected astrocytes were plated in 48-well tissue culture plates at a density of 0.15 × 106 cells/well and allowed to recover for 48 h prior to treatment with IL-1β (20 ng/...
atKRT14/16/17proximal genomic region in MCF7 cells. CTCF motif orientations of each peak is labeled with arrows.Y-axis represents signal intensity of each track.eCTCF binding events at binding sites 1 and 5 inc. Each bar represents mean ± SD of fold enrichment normalized to IgG from...
[78], IgG4-related disease [8], pre-eclampsia [67], squamous cell carcinoma [37], chronic kidney disease [53], myocardial infarction [35,81]. Yang et al. [78] also demonstrated that increased plasma CXCL12 levels in postmenopausal osteoporosis is significantly correlated to pain severity ...
The signature cytokines produced by Th2 (IL-4) and Th17 (IL-17) cells are implicated in inflammatory processes involving eosinophil and neutrophil activation, respec- tively [17, 20, 21]. With regard to adaptive humoral immune response, the production of IgG, IgA and IgE neutralizing ...