Lopez T, Hanahan D. Elevated levels of IGF-1 receptor convey inva- sive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 2002;1:339-53.Elevated levels of IGF-1 receptor convey invasive and metastatic capability in mouse model of pancreatic islet ...
Elevated IGF-I levels increase the risk of developing prostate cancerdoi:10.1038/ncpendmet1030NoneNature Clinical Practice Endocrinology & Metabolism
It is not known how many subjects with increased IGF-1 levels have acromegaly. We aimed to assess the prevalence of acromegaly in primary care by screening for elevated IGF-1 levels. DOI: 10.1111/j.1365-2265.2008.03221.x 年份: 2008 ...
Plasma levels of insulin-like growth factor-1 (IGF-1) were significantly elevated in high-growth mice at all ages studied (3 wk-6 mo); IGF-binding proteins were also elevated. Skin biopsies were obtained from mice aged 3, 6, and 9 wk under halothane anesthesia. Mice were killed at 6 ...
Elevated expression levels of serumIGF‐1,TNF‐α andVEGF165might exacerbate type 2DN.doi:10.1111/jdi.12542Li, XiangWu, Ting-TingChen, JuanQiu, WenJohn Wiley and Sons Inc.Journal of diabetes investigationElevated expression levels of serum insulin-like growth factor-1,tumor necrosis factor-αand...
Elevated serum IGF-I, but unaltered sex steroid levels, in healthy boys with pubertal gynaecomastia. Clin Endocri- nol (Oxf). 2014;80:691- 698.Mieritz MG, Sorensen K, Aksglaede L, et al. Elevated serum IGF-I, but unaltered sex steroid levels, in healthy boys with pubertal gynae- ...
While neonatal serum levels of IGF-I have been evaluated with regard to overall fetal growth and elevations are tightly associated with fetal macro- somia, 16 to our knowledge, the associa- tion with fetal HCM has not been reported. The objective of this study was to evaluate the incidence ...
2015: Women with osteoarthritis have elevated synovial fluid levels of insulin-like growth factor (IGF)-1 and IGF-binding protein-3 Journal of Immunoassay and Immunochemistry 36(3): 284-294 Hills, F.A.; Crawford, R.; Harding, S.; Farkas, A.; Chard, T. 1994: The effects of labor on...
RESULTS: For female subjects, total IGF-I (MA(+) 1.2 mU/l vs. MA(-) 1.4 mU/l, P = 0.03) and free IGF-I levels (MA(+) 1,767 ng/l vs. MA(-) 2010 ng/l, P = 0.002) were lower, whereas the free androgen index (MA(+) 2.4 vs. MA(-) 2.0, P = 0.03) was higher in...
After 1week of fasting, the expression of all studied genes was reduced in both diploids and triploids, while the expressions levels were higher in triploids than in diploids. These results suggest that the elevated expression of GH/IGF axis genes in triploids plays a crucial role in the ...