A two-month old infant who presented for elective craniosynostosis repair was noted to have an elevated prothrombin time (PT) with a normal activated partial thromboplastin time (aPTT) on preoperative labs. The infant had no clinical history or reported family history of bleeding disorders, ...
Under normal conditions, the AP is constitutively active through spontaneous hydrolysis of the thioester bond in C3 and the formation of the initial fluid phase C3 convertase, C3(H2O)Bb, which cleaves C3 into C3a and C3b55. CFH promotes decay of the alternative and classical pathway convertase...
5a, b, c). Further, serum syndecan-1 levels correlated significantly with YFV NS1, TEER values, sex (male), hospitalization, viral load, parameters of liver impairment (AST, ALT, creatinine, TB, DB, and IB), kidney dysfunction (creatinine), coagulopathy (fibrinogen, PT/INR, aPTT), and ...
Although a significant correlation between overt bleeding and abnormal PT/INR and APTT (observed in 20鈥 37% cases) could not be demonstrated, a good correlation existed between normal screening coagulation tests and the absence of bleeding complications. Elevated D-Dimer and FDP levels in almost ...
His INR and aPTT trended downward, reaching normal levels 5 days after admission. Conclusion. Dabigatran is contraindicated in patients with severe kidney insufficiency as it is predominantly excreted via the kidney (~80%). Elderly patients over 75 and patients with chronic renal impairment should ...
In contrast, antiphosphatidylserine/prothrombin (aPS/PT) IgM antibody levels, but not IgG, were significantly higher in the high LAC titer group. Conclusions: The degree of prolongation of the APTT/DRVVT screening time is not correlated with the LAC titer. Only aPS/PT IgM antibodies l...
APTTProthrombin timePTSpecialized coagulation assayChronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and emphysematous alveolar destruction. In this study, we have investigated whether chitotriosidase (ChTRase) and acidic mammalian chitinase, two chitinases with ...
A novel non-invasive index using AFP and APTT is associated with liver fibrosis in patients with chronic hepatitis B infection: A retrospective cohort study. BMJ Open 2015, 5, e008032. [Google Scholar] [CrossRef] Wang, H.W.; Peng, C.Y.; Lai, H.C.; Su, W.P.; Lin, C.H.; ...