A model of the cardiac conduction system is considered. The model provides an insight into the electrical processes in the myocardium under normal and pathological conditions. The model takes into account the involvement of the atria in generating the sinus rhythm of the heart and the sinus rhythm...
are seen in the SA node and a few other conductive cells in the heart. Since the SA node is the pacemaker, it reaches threshold faster than any other component of the conduction system. It will initiate the impulses spreading to the other conducting cells. ...
Normally, the only pathway available for action potentials to enter the ventricles is through a specialized region of cells (atrioventricular node, or AV node) located in the inferior-posterior region of the interatrial septum. The AV node is a highly specialized conducting tissue (cardiac, not ne...
Within the most upregulated response pathways, we also explored signaling responses previously implicated in the modulation of cardiac conduction. The Notch signaling pathway, which plays an important role in conduction system development31,32,33, was present at both timepoints (Fig.5a). Furthermore,...
without a predefined hypothesis12. A previous GWAS meta-analysis for the spQRSTa (N = 13,826) identified 3 independent loci, with candidate genes involved in cardiac conduction and development13. However, this study was limited by a small sample size, and no GWAS has investigated the fQR...
Electrical phenomena play an important role in numerous biological processes including cellular signaling, early embryogenesis, tissue repair and remodeling, and growth of organisms. Electrical and magnetic effects have been studied on a variety of stimu
Trpm4-Linked Isolated Cardiac Conduction Defects: Bad Trafficking Causes Electrical Gridlock Mills RW, Milan DJ (2010) TRPM4-linked isolated cardiac conduction defects: bad trafficking causes electrical gridlock. Circ Cardiovasc Genet 3:311–313. : 10.1161/CIRCGENETICS.110.957670......
constructionofcardiacatrioventricularelectricalconductionpathwaybyrabbitbone 系统标签: 间充质干细胞电传导骨髓mesenchymal心脏atrioventricular 中国组织工程研究第18卷第41期2014–10–01出版 ChineseJournalofTissueEngineeringResearchOctober1,2014Vol.18,No.41 ISSN2095-4344CN21-1581/RCODEN:ZLKHAH 6597 .CRTER 周浩粤,...
This study investigated the effects of individual canine cardiac nerve stimulation on atrioventricular conductions as measured by His bundle electrograms. ... LE Rinkema,JX Thomas,WC Randall - 《Journal of the Autonomic Nervous System》 被引量: 32发表: 1982年 Role of the spinal trigeminal nucleus...
(Fig.1a, Family#1). The closest gene upstream of the deletion,PITX2, is located 1 Mb away while the nearest gene downstream—FAM241a—is at a distance of 500 kb from the deletion (Fig.1b). We then investigated additional unrelated familial cases with similar cardiac phenotypes ...