The sequence of electrical activation in the heart significantly affects the pattern and effectiveness of contraction. Whereas the normal heart contracts in a coordinated manner, in heart failure (HF), abnormal electrical activation, most commonly left bundle branch block (LBBB), can substantially ...
The heart has a regulatory system, known as the intrinsic conduction system, that determines the pace of the heartbeat. Learn about the intrinsic conduction system, including the SA node, AV node, the bundle of His, bundle branches, and Purkinje fibers, an...
The Prognostic Significance of Bundle Branch Block in High‐Risk Chronic Stable Vascular Disease Patients: A Report from the HOPE Trial In multivariate models, LBBB remained an independent predictor of heart failure, sudden death, CV death, and all-cause death (P ≤ 0.002 for all). ... G Su...
Epicardial activation and recovery were assessed by ECGI in 22 normal subjects, 4 subjects with bundle branch block (BBB) and 4 with long-QT syndrome (LQTS). We compared characteristics between the ventricles [left ventricle (LV) and right ventricle (RV)], sexes, and age groups (<50/≥50...
The sinoatrial (sinus) node (1) initiates an electrical impulse that flows through the right and left atria (2), making them contract. When the electrical impulse reaches the atrioventricular node (3), it is delayed slightly. The impulse then travels down the bundle of His (4), which divid...
In these topics Biology of the Heart Bundle Branch Block Overview of Abnormal Heart Rhythms Overview of Heart Block
Figure 9. (a) In a second-degree or partial block, one-half of the P waves are not followed by the QRS complex and T waves while the other half are. (b) In atrial fibrillation, the electrical pattern is abnormal prior to the QRS complex, and the frequency between the QRS complexes ...
1983: Determination of the left bundle branch refractoriness by distal his bundle pacing in patients with left bundle branch block Pacing and Clinical Electrophysiology: Pace 6(6): 1245-1251 Valere P E.; Guerot, C.; Tricot, R. 1971: Recording of electrical potentials in the bundle of his ...
in the CUPID 1 trial a greater proportion of empty viral capsids among total viral particle dose was observed, when compared to the CUPID 2. This could be of relevance, since it was previously shown that empty viral capsids can block the neutralizing activity of the serum antibodies, leaving...
if the intrinsic rate of the ectopic pacemaker rises above that of the sinus node; if the sinus node rate falls below that of the ectopic pacemaker; or when a normal sinus node impulse is prevented from being conducted through the heart (heart block) leaving the ectopic pacemaker to fire at...