Reshetnikova G, Barkan R, Popov B, Nikolsky N, Chang LS (2000) Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, cdk2 phosphorylation and nuclear accumulation of the retinoblastoma protein-related p107 protein. Exp Cell Res 259:35–53...
Simultaneous inhibition of MEK and CDK4 leads to potent apoptosis in human melanoma cells. 来自 掌桥科研 喜欢 0 阅读量: 90 作者:J Li,M Xu,Z Yang,A Li,J Dong 摘要: Deregulation of -RAF-MEK-and -cycylin D:/6-RB pathways is important for . Chemotherapeutic agents targeting both pathways...
Cell cycle, apoptosis and the protein levels of CDKs and CDKNs were performed to evaluate HCC cell growth. Inhibition of HDAC1/2 by RNAi was further investigated. Results Combined inhibition of HDAC1/2 led to HCC cell morphology changes, growth inhibition, cell cycle blockage and apoptosis in ...
Anti-CDK4 anti-sense plasmid was constructed and used to transfect V79-8 cells. Clones of transfected cells (V79-8-asCDK4) were examined, in comparison with V79-8 cells, to determine its growth curve, cell doubling-time (GT), the level of CDK4 gene expression and the levels of ...
The authors further suggest to conduct more in depth studies to explore the roles of CD1d and type II NKT cells in human diseases.EBSCO_AspInflammatory Bowel Disease Monitor
The article reports the move by bank ABN Amro in late September 2015 to appoint its own investment bank, as well as Citibank, Goldman Sachs, HSBC, Morgan Stanley, and Union Bank of Switzerland (UBS) as joint bookrunners of its inaugural additional tier one (AT1) deal. Also cited are ...