The participant must be informed of the degree of likelihood that the test result will be wrong (and how frequently this is expected to occur), potentially resulting in inaccurate treatment assignment. The participant should understand the likely consequences should an erroneous treatment assignment ...
Performance assessments based on re-use of data used in model building are informative only when appropriate internal validation strategies are used. Despite standardization of assays and attempts to avoid model overfitting, a predictor model will nearly always fit better to the data used to develop ...