AntibodySystem由具有30多年蛋白抗体开发经验的专家创立于法国,专注于生命科学和生物制药领域研究,总部位于法国斯特拉斯堡市。AntibodySystem自主开发了高效、高产的真核重组表达系统,利用该系统生产了高质量的重组蛋白、抗体产品。目前产品包括药物靶点蛋白以及对照抗体药物、Invivo功能性抗体、SAA系列流式抗体、PEG抗体、磷酸...
温州科淼生物科技有限公司(Whenzhou KeMiao Biological Technology Co.,Ltd)是一家专业从事“产品研发生产,市场销售,技术服务”为一体的高科技生物技术公司,致力于为科研实验服务,主要产品为抗体、试剂盒、细胞、生化试剂等其他相关试剂。 抗体(antibody)是生物体在抗原物质刺激下,由B细胞分化成的浆细胞所产生的、可与...
Antibody 克隆号 RM419 抗原 A peptide corresponding to epidermal growth factor receptor variant III (EGFRvIII) (aa 1-100). 查看免疫原 偶联物 Unconjugated 形式 Liquid 浓度 0.02 mg/mL 纯化类型 Protein A 保存液 PBS with 50% glycerol, 1% BSA ...
双特异性抗体(bispecificantibody)是一种人工合成的可以同时结合两种抗原表位的特殊抗体,相较于单克隆抗体可以介导更多生物学功能,例如将细胞毒性T细胞募集到肿瘤细胞附近,同时抑制两个信号转导途径,增强靶向表达两种抗原的细胞的特异性,跨血脑屏障递送抗体;临床使用成本也远低于两个单药联合疗法。双特异性抗体在多个疾病...
The present invention relates to an antibody that specifically binds to EGFRvIII (epidermal growth factor receptor variant III), a nucleic acid encoding said antibody, a vector comprising said nucleic acid, a host cell, a method for producing said antibody and said antibody as an active ingredient...
[1]Novel EGFRvIII-selective antibody-drug conjugate REGN3124-PBD is strongly efficacious against orthotopic glioblastoma multiforme patient-derived xenografts. Abstract: P134, Presented at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics. October 7-10. ...
We showed that EGFR-vIII is very rare in HNSCC, while the common R521K polymorphism abolishes antibody-dependent cellular cytotoxicity and in vivo antitumor effect of cetuximab. This selectivity was not reflected in immunophenotype or survival data of HNSCC patients, suggesting a more complex ...
(SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L, the biotinylated protein can bind to the SA beads irreversibly. The pre-coupled beads are ready to use for capturing anti-EGFRvIII antibody from your sample with high ...
This mutated recombinant antibody, called RAbDMvIII, specifically detects EGFRvIII expression in EGFRvIII expressing cell lines as well as in EGFRvIII expressing GBM primary tissue by western blot, immunohistochemistry (IHC) and immunofluorescence (IF) and FACS analysis. It does not recognize wild type...
EGFRvIII;Rabbit Anti-EGFRvIII antibody 中文名: EGFRvIII 中文别名: EGFRVIII蛋白;表皮生长因子受体III型突变体抗体;ANTI-EGFRVIII ANTIBODY-B-表皮生长因子受体III型突变体抗体 CBNumber: CB95780414 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商17 ...