5. Mitsudomi, T. and Y. Yatabe,Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer.Cancer Science, 2010.99(12): p. 1817-1824. 6. Sharma, S.V., et al.,Epidermal gro...
在所有39名携带EGFR突变的参与者中,TP53、KRAS、PIK3CA、APC和FBXW7也发生了突变。 Zhang Y, Li S, Lyu Z, et al. Theco-mutation ofEGFRand tumor-related genes leads to a worse prognosis and a higher level of tumor mutational burden in ...
Lung cancer is the leading cause of cancer related deaths in the United States, with an estimated 158, 040 deaths in 2015, accounting for 27% of all cancer deaths. Recent research has identified several important molecular driver oncogenes, including epidermal growth factor receptor (EGFR). EGFR...
亚洲人群非小细胞肺癌(non-small cell lung cancer,NSCLC)表皮生长因子受体(epidermal growth factor receptor,EGFR)突变发生率显著高于西方人群。近年来,以针对程序性死亡因子1(programmed cell death 1,PD-1)及程序性死亡因子配体1(programmed cell death ligand 1,PD-L1)抗体药物为代表的免疫治疗已成为晚期NSCLC临床...
5. Mitsudomi, T. and Y. Yatabe,Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer.Cancer Science, 2010.99(12): p...
Lee KH , et al. Nivolumab plus ipilimumab versus chemotherapy as first-line treatment in advanced non-small-cell lung cancer with high tumour mutational burden: patient-reported outcomes results from the randomised, open-label, phase III CheckMate 227 trial. Eur J Cancer. 2019 Jul;116:137-147...
[14]Jao K, Tomasini P, Kamel-Reid S, et al. The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer. Lung Cancer. 2018 Sep;123:22-29. DOI: 10.1016/j.lungcan.2018.06.023 *本材料由阿斯利康提供，仅供医疗卫生专业人士进行医学...
[12] Saito G , Ebata T , Ishiwata T , et al. Risk factors for skeletal-related events in non-small cell lung cancer patients treated with bone-modifying agents[J]. Supportive Care in Cancer, 2021, 29(7).
Lung cancer is the leading global cause of cancer-related mortality. Inter-individual variability in treatment response and prognosis has been associated w... JG Carneiro,PG Couto,L Bastos-Rodrigues,... - 《Genetics Research》 被引量: 33发表: 2014年 Roles of EGFR and KRAS Mutations in the ...
Personalized treatment of advanced non-small cell lung cancer Lung cancer is the leading cause of cancer-related mortality worldwide. Recent scientific progress has identified a tremendous genetic heterogeneity in his... J Köhler,M Schuler - 《Der Onkologe》 被引量: 6发表: 2011年 ...