There were seven patients found to carry a triple mutation: four of them were male; two, smokers; age range, 47–76 years. There were five patients who harboured double EGFR mutations and one patient (76 years old, female) who had double PIK3CA mutations. Three triple-mutation specimens ha...
is generally in the range from 0.1 to 100 mg/kg of body weight of the recipient (mammal) per day and particularly typically in the range from 1 to 10 mg/kg of body weight per day. Thus, the actual amount per day for an adult mammal weighing 70 kg would usually be between 70 and ...
Figure 2.Flow-chart of patients enrolled in the PLUREX study and involved in the analysis of EGFR mutational status on plasma and urine samples. Abbreviations: ctDNA, cell-free tumor DNA; TKI, Tyrosine kinase inhibitor; gen., generation. ...
(rw) de-identified clinicogenomic database. Patients who initiated therapy forEGFR-mutated aNSCLC between January 2014 and December 2020 were identified. Clinical outcomes were evaluated byTP53-mutational status. In 356 eligibleEGFR-mutated aNSCLC patients (median age 68 years), 210 (59.0%) had...