Zhang Y, Li S, Lyu Z, et al. Theco-mutation ofEGFRand tumor-related genes leads to a worse prognosis and a higher level of tumor mutational burden in Chinese non-small cell lung cancer patients.J Thorac Dis. 2022;14(1):185-193...
prognosisNon-small-cell lung cancer (NSCLC) has entered the age of individual treatment, and increasing point mutations of specific oncogenes and rearrangement of some chromosomes are biomarkers used to predict the therapeutic effect of targeted therapy. At present, there is a consens...
3. Juliana Eng et al.Impact of Concurrent PIK3CA Mutations on Response to EGFR Tyrosine Kinase Inhibition in EGFR-Mutant Lung Cancers and on Prognosis in Oncogene-Driven Lung Adenocarcinomas.2016 4. Matteo Canale et al.Impact of ...
In addition, we review the comparison of response to chemotherapy betweenEGFRmutations in exon 19 and in exon 21 and the predictive role of p.T790M mutation. 展开 关键词: epidermal growth factor receptor prediction prognosis DOI: 10.2147/DDDT.S69690 被引量: 33 ...
[3]Zhang Y, Li S, Lyu Z, et al. The co-mutation of EGFR and tumor-related genes leads to a worse prognosis and a higher level of tumor mutational burden in Chinese non-small cell lung cancer patients[J]. Journal of Thoracic Disease, 2022, 14(1): 185-193. DOI: 10.21037/jtd-21...
AXL is a member of the receptor tyrosine kinase family, which is involved in tumor growth, invasion and metastasis. High expression of AXL was reported to be associated with poor prognosis in several types of cancer, including NSCLC. Compared to those with wild-type EGFR, AXL was overexpressed...
development of a rash might be a marker of patients with an intact infl ammatory or immune response that portends improved prognosis irrespective of specifi c treatment. Rash as a predictive marker would be diffi cult to incorporate into routine practice. Erlotinib-induced rash is not present be...
Poor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer. Cancer Manag Res. 2019 Nov 13;11:9621-9630. [7] 解立武, 王晶. 肺腺癌原发T790M突变的临床预后." 中国药物与临床 21.3(2021):3. [8] Li W , Qiu T , Guo L , et...
Effect of epidermal growth factor receptor mutation on early-stage non-small cell lung cancer according to the 8th TNM classification EGFR突变在早期非小细胞肺癌中的预后效应--基于第八版TNM分期 Highlights Effect of EGFR mutations on the prognosis of stage 0–...
mutation. The presence of this mutation raises the possibility of employing EGFR inhibitors as potential therapeutic agents to improve the otherwise dismal prognosis of patients with pulmonary choriocarcinoma. The present case underscores the importance of EGFR scre...