LI YC,XU WY,TAN TZ,et al.131I-Recombi-nant Human EGF Has Antitumor Effects AgainstMCF-7 Human Breast Cancer Xenografts WithLow Levels of EGFR. Nuclear Medicine and Biology . 2004LI YC,XU WY,TAN TZ,et al.131I-Recombi-nant Human EGF Has Antitumor Effects AgainstMCF-7 Human Breast Cancer...
Cell lines expressing low EGFR levels were most highly protected by EGF, indicating that normal (low EGFR-expressing) tissue may be selectively protected by EGF in vivo. P-glycoprotein did not confer resistance to TGF-alpha-PE40, and toxicity was unaffected by multidrug resistance-modulating ...
Measurement uncertainty of eGFR at low creatinine levels: Be careful to not overestimate David,Parry - 《Clinical Biochemistry》 被引量: 3发表: 2010年 Measurement uncertainty of eGFR at low creatinine levels: Be careful to not overestimate Parry,D. - CLINICAL BIOCHEMISTRY -OTTAWA THEN NEW YORK- ...
(A, B) Survival curves for each trial arm in N9831 patients with low ( A ) or high ( B ) EGFR levels. Full size image The association between EGFR status (high vs low) and DFS was evaluated with univariable and multivariable models (Table 1) for each of the three treatment arms. ...
Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid treatment in SNU-C5 cells inhibited EGF-induced phosphorylation of EGFR and suppressed ...
•InadditiontothelowfrequencyofEGFRpositivityinourpatientcohort,notallCTCsofindividualcasescouldbeclassifiedasEGFRoverexpressing,revealingasubstantialheterogeneityinEGFRlevelsamongCTCsfromthesamepatient.ThesevaryingexpressionlevelspresumablyreflectintratumoralheterogeneityofEGFRexpression.•Unliketheoverexpressionofthe...
The simplest hypothesis to account for the development of resistance to EGFR blockade is that rare cells with KRAS mutations pre-exist at low levels in tumours with ostensibly wild-type KRAS genes. Although this hypothesis would seem readily testable, there is no evidence in pre-clinical models ...
A significant positive correlation was observed between AEG‐1, TS, ERCC1, EGFR, and VEGF gene expression levels in CRC cell lines, and low AEG‐1 ... LW Lin,PS Lai,YY Chen,... - 《Pathology International》 被引量: 0发表: 2021年 ...
normal colon tissues and the low levels of GRHL1 correlated with better overall survival of cancer patients. In accordance with this, knockdown of GRHL1 inhibited the proliferation of human colon cancer cells9. These studies indicated that the functions of GRHL1 were different depending on the ...
Low levels of Ephexin1 prevents interactions between EphA2 and EGFR Ephexin1 has been shown to associate with the kinase domain of EphA4 [29]. Since the kinase domain of EphA2 is very similar to that of EphA4 (76.5% identity and 95.0% positive by FASTA: https://www.ebi.ac.uk/Tools...