"Momentum is clearly building," saidNwamaka D. Eneanya, MD, a nephrologist at the University of Pennsylvania in Philadelphia, and lead author of a commentary published a little over a year ago that laid out the case for reconsidering how to calculate eGFR in African Americans (JAMA2019;322:...
Your test result typically includes a reference range for what the laboratory considers normal eGFR levels. For eGFR based on creatinine levels, many laboratories list separate reference ranges for African Americans and non-African Americans because some prior studies have found varying eGFR levels among...
This observed frequency is higher than that in the African Americans from the southwestern United States in 1000 Genomes (MAF = 1.6%), but substantially lower than in continental African populations (MAF 10.1–13.9%). Screening for sickle cell in the United States Military has undergone ...
Association of Race-Based vs. Race-Free eGFR With Nutritional Status, Mortality, and ESKD in African Americans With CKDdoi:10.1681/ASN.20223311S1299bSahar AminThe University of Tennessee Health Science Center College of Medicine, Memphis, TNAtif Ibrahim...
Given that implicit and explicit bias factors into provider communications and decisions, this could come into play as more Americans identify as mixed race and lead to less transparency in those recommendations, she cautioned. There is no guidance for mixed race in the eGFR and there was a rou...
Introduction: Mutations in EGFR and KRAS can impact treatment decisions for patients with NSCLC. The incidence of these mutations varies, and it is unclear whether there is a decreased frequency among African Americans (AfAs). Methods: We performed a retrospective chart review of 513 NSCLC patients...
It occurs at the rate of 10–15% in North Americans and Europeans, 19% in African-Americans, 20–30% in various East Asian series including Chinese, Koreans, and Japanese. Frequency of EGFR mutations in India however remains sparsely explored. Methodology/Principal Findings: We report 23% ...
IntroductionMutations in EGFR and KRAS can impact treatment decisions for patients with NSCLC. The incidence of these mutations varies, and it is unclear whether there is a decreased frequency among African Americans (AfAs).Joshua BaumlRosemarie Mick...
This study included 954 African Americans (AA), 781 American Indians (AI), 614 European Americans (EA) and 1,611 Mexican Americans (MA). A total of 3,960 FIND participants were genotyped for 6,000 single nucleotide polymorphisms (SNPs) using the Illumina Linkage IVb panel. GFR was ...
Analysis was performed on two samples of Indigenous Americans genotyped on genome-wide SNP arrays. Using four tests for natural selection-locus-specific branch length (LSBL), ratio of heterozygosities (lnRH), Tajima's D difference, and extended haplotype homozygosity (EHH)-we identified 14 ...