Results The 9 trusts identified 314 patients in whom specimens had been sent for EGFR mutation testing; 161 (51%) males; average age 69 years (34-91); 60% were WHO performance status 0-1; 95% were current or ex-smokers; 47% (149) had stage 4 disease. 60 (19%) were female with...
Two researchers performed literature screening, data extraction (the first author, publication time, the country where the author coming from, study type, sample size, stage of NSCLC, sex, average age, treatment regimen, ECOG PS score, median follow-up time, pathological type, gene mutation type...
1. This standard curve is used to determine the amount in an unknown sample. The standard curve is generated by plotting the average O.D. (450 nm) obtained for each of the six standard concentrations on the vertical (Y) axis versus the corresponding concentration on the horizontal (X) axis...
The 382 patients included 175 men and 207 women with an average age of 62.8 years (median, 64.5 years; range, 26–91 years). Clinicopathologic informations were obtained from the medical records and pathology reports. The patients' characteristics are shown in Table 1. This study was approved ...
Similarly, average MET H-score in IHC-positive patients was 264 but only 78 in IHC-negative patients; breakdown by mutation type is also provided (Extended Data Fig. 2). Of the 20 patients included in this analysis, 10 had a confirmed PR (Fig. 3). In the 10 patients who were IHC-...
Their average gray scale values were 148.49±13.05 and 155.65±14.86, respectively, which showed a significant difference (t=2.13, P=0.04). There was no obvious difference between males and females (149.01±13.70 and 147.40±11.76, t=0.54, P=0.59). No significant association was observed ...
The average age at diagnosis was 60.6 years (range, 33–78 years), and the majority of participants were female (26/47, 55.3%), never-smokers (36/47, 76.6%), and had an ECOG performance status of 0 (29/47, 61.7%). Among the enrolled participants, 28 (59.6%) had the Ex19Del ...
Tetramer-positive cells were quantified by flow cytometry and expressed as percent of CD8+ T cells. Averages were calculated as geometric means. For non-parametric distribution of samples, p-values were calculated by Kruskal-Wallis and two-tailed exact Wilcoxon-Mann-Whitney tests using SPSS ...
The average gene expression in the TCGA provisional dataset confirmed that EGFR is elevated in bladder cancer and specifically in the ‘basal’ subtype classes 3 and 4 (p < 0.01, ANOVA). The dataset also confirmed that HER2 is elevated in bladder cancer compared to normal urothelium, mor...
They consisted of 302 men and 167 women ranging in age from 19 to 91 (average 66.2) years. One hundred seventy three had stage IA disease, 86 had stage IB, 11 had stage IIA, 54 had stage IIB, 73 had stage IIIA, 50 had stage IIIB, and 22 had stage IV disease. There were 138 ...