Blood-based testingCobas assayEGFR mutationErlotinibObjective: Patients with advanced non-small-cell lung cancer (NSCLC) with an adenocarcinoma component are recommended to undergo epidermal growth factor receptor (EGFR) mutation testing when being considered for EGFR targeted therapy. We conducted an ...
Incubated samples were analyzed by an LC-MS/MS system to detect remaining test compounds. Extraction ratio (ER) was calculated according to the equation below:ER=CLint,pred/Qh+CLint,pred Here: CLint, pred: Predicted intrinsic clearance (mL/min/kg) [41]. Qh: Hepatic blood flow CLint, pred...
Immunoglobulins are absorbed into the calfs blood through the intestine and this absorption ceases approximately 24 h after birth due to the rapid modification of the gut NU6300 enterocytes, meaning that early administration of colostrum is essential [3]. This transfer of Ig from the dam colostrum...
Impact of Sample Collection Method for EGFR Mutation Testing: Results of Blood-Based and Tissue-Based cobas EGFR Mutation Testing in the Treatment of Locally Advanced or Metastatic NSCLC in the US Poulios N1, Hristova-Neeley D2, Gavaghan M2...