Effective broadly-acting antiviral countermeasures are urgently needed to prepare for future emerging CoVs, as vaccine development is not compatible with a rapid response to a newly emerging virus. The green tea catechin, epigallocatechin gallate (EGCG), has broad-spectrum antiviral activity, although ...
The catechin, epigallocatechin gallate (EGCG), an active compound found in green tea, holds neuroprotective features and is known for its anti-inflammatory potential. The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that exists in two functionally distinct co...
www.nature.com/scientificreports OPEN The green tea catechin EGCG provides proof‑of‑concept for a pan‑coronavirus attachment inhibitor Emmanuelle V. LeBlanc & Che C. Colpitts* The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS- CoV-2...
研究成果发表在 Antioxidants 期刊题为“EGCG, a Green Tea Compound, Increases NO Production and Has Antioxidant Action in a Static and Shear Stress In Vitro Model of Preeclampsia”。 首先,与健康(HP )孕妇组相比,与 PE 血浆一起孵育的 EC 产生的 NO 更少(PE:82.26 ± 4.89 vs. HP:100.00 ± 3.67...
Recently, EGCG, a green tea polyphenol, was reported to inhibit SARS-CoV-2 3CL-protease, however the effect of EGCG on coronavirus replication is unknown. In this report, human coronavirus HCoV-OC43 (beta coronavirus) and HCoV-229E (alpha coronavirus) were used to examine the effect of ...
近日,华中农业大学田静联合瑞士苏黎世联邦理工学院和德国耶拿大学的研究人员在" Aging "期刊发表了一篇题为" Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition "的研究论文。 该研究显示,绿茶中的儿茶素能使线虫寿命更长,更健康。但得出一个颠覆...
Epigallatocathechin-3-gallate (EGCG) is the most abundant polyphenol found in green tea leaves (A. Islam, 2012). EGCG appears to have many actions on the brain, including its function as a powerful antioxidant, preventing oxidative damage in healthy cells. It also affects a wide array of ...
持续两周摄入绿茶能够显著改善长期吸烟者血流介导的内皮依赖性血管舒张,提高其外周血管内皮祖细胞数,详见“KimW,JeongMH,ChoSH,YunJH,ChaeHJ,etal.(2006)Effectofgreenteaconsumptiononendothelialfunctionandcirculatingendothelialprogenitorcellsinchronicsmokers.Circulationjournal:officialjournaloftheJapaneseCirculationSociety70...
Triple-negative breast cancer (TNBC) cells’ secretome can induce a pro-inflammatory phenotype in human adipose-derived mesenchymal stem cells (hADMSC). This can be prevented by the green tea polyphenol epigallocatechin-3-gallate (EGCG). The impact of EGCG on the paracrine regulation that the ext...
2. Responders vs. Non-Responders Clinically relevant cytotoxic levels of EGCG in plasma [15] may not be reached in vivo through oral ingestion of green tea, green tea extracts or pure EGCG; health promoting targets of this polyphenol will then take place through other pathways. The decrease ...