More precisely, this column hopes to better inform readers about the mechanism of action, administration, dosage, adverse effects, and possible alternatives for each particular drug discussed, This article highlights the use of eflornithine as a topical treatment for hirsutism....
After a short description of trypanosomiasis and the current treatment, the mechanism of action of eflornithine is discussed, some clinical data is given and attention is paid to recently discovered analogues of eflornithine. Some examples of combination therapy with eflornithine and possible applications...
Females and Males of Reproductive PotentialBased on animal data and mechanism of action, eflornithine can cause fetal harm when administered to a pregnant woman. Verify pregnancy status in females of reproductive potential prior to initiating therapy.Advise females of reproductive potential to use ...
Eflornithine (伪-difluoromethylornithine; DFMO) is a recently developed drug against African trypanosomiasis (sleeping sickness). After a short description of trypanosomiasis and the current treatment, the mechanism of action of eflornithine is discussed, some clinical data is given and attention is ...
Focuses on the treatment of hirsutism in women. Brief information on hirsutism; Effectiveness of oral contraceptives and antiandrogens in treating hirsutism; Mechanism of action of eflornithine hydrochloride.doi:Ornithine decarboxylase inhibitors, generalEscobarmorreale H.F...