Hormonal contraceptives and antiepileptic drugs (AEDs) interact at the level of the liver’s cytochrome P450 (CYP450) enzyme pathway. Estrogens and progestins are metabolized by CYP450 3A4 [1–3]. Many AEDs, such as phenytoin, phenobarbital, oxcarbazepine, topiramate and carbamazepine are inducers...
Progestin-only pillEfficacySafetyCycle controlThis study was performed to assess the contraceptive efficacy of the drospirenone (DRSP)-only pill and to provide information regarding its safety and cycle-control profile. This prospective, multicenter, noncomparative study was conducted at 41 European sites...
The mini-pill or progestogen-only pill, as well as the contraceptive injection, are the safest birth control methods in these cases. Even though the mini-pill is not as reliable as the combined pill, if used carefully the failure rate is low. The combined pill is unadvisable because it ca...
Progestin-only pills do not increase the risk of venous thromboembolic events, stroke and myocardial infarction but are associated with a poor cycle control. A novel estrogen-free pill containing only drospirenone (DRSP) was developed to improve bleeding pattern, tolerability and acceptance without ...
Progesterone/progestin-only pill24/4-day regimenEfficacySafetyScheduled bleedingTo evaluate contraceptive effectiveness and safety of oral drospirenone 4mg 24/4-day regimen in the United States.doi:10.1016/j.conx.2020.100020Thomas Kimble aAnne E. Burke b...
An increasing number of women in Europe and in the USA use LARCs, and the LNG-IUS and Cu-IUDs are the most popular contraceptives in this class [2-4] . The same is true for women with intercurrent health problems, for whom combined contraceptives containing estrogen and progestin may ...
In Japan, DNG is a regularly used progestin-only agent; however, it was only indicated for endometriosis before it was approved for dysmenorrhea. There are two types of dysmenorrhea: primary dysmenorrhea and secondary dysmenorrhea. In secondary dysmenorrhea, dysmenorrhea appears as a secondary symptom...
ContraceptionProgestin-only pillEfficacySafetyCycle controlObjectives: This study was performed to assess the contraceptive efficacy of the drospirenone (DRSP)-only pill and to provide information regarding its safety and cycle-control profile.Archer, David F.Ahrendt, Hans-JoachimDrouin, Dominique...