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Thus, short-term methotrexate discontinuation could be considered in cases of infections or surgery. Potential limitations of the study include only assessing the effect of a temporary methotrexate discontinuation on the vaccine’s antibody production after a flu shot. Because antibody production does not...
Most recently, the Flu Watch Cohort Study10has investigated whether pre-existing T-cell responses targeting internal viral proteins could provide protective immunity against pandemic and seasonal influenza. NP is one of the most conserved internal influenza antigens; even the most divergent protein seque...
Once 52 eligible Covid cases are detected from the trial, which aims to enroll as many as 30,000 people, researchers will conduct interim analysis on the shot’s efficacy against the both the original version of the virus and its variants, including the highly-infectious delta strain. “I’...
Sensitive detection of IgG antibodies against SARS-CoV-2 is important to assessing immune responses to viral infection or vaccination and immunity duration. Antibody assays using non-invasive body fluids such as saliva could facilitate mass testing including young children, elderly and those who resist...
The trial was conducted among 828 people between December 2022 and February 2023. This is a far lower number of participants than Pfizer’sphase3 study, which involved over 40,000 individuals. The small scale of Kostaive trial has raised questions about its validit...
(2023) demonstrated the synergistic potential of the PARP inhibitor niraparib and DOX against ovarian cancer. Both drugs are encapsulated in highly stable liposomes containing folate to target FRα overexpressed on the surface of ovarian cancer cells [144]. Using this approach, the targeted delivery...
These newly updated vaccines replaced the XBB-focused vaccines that were authorized in September 2023. An updated, JN.1-focused Novavax vaccine is expected to be authorized by the start of the vaccination season for people ages 12 and older....