Patients who had Mediterranean fever variants but could not be classified as FMF according to Tel-Hashomer criteria were excluded.Results:There is no controlled trial on the efficacy and safety of biologics in FMF. Fifty-nine (32 female and 27 male) patients with FMF who had been treated ...
Therefore, conventional systemic therapies are often contraindicated with biologics appearing as mainstay for moderate‐to﹕evere disease. However, data on efficacy and safety of biologics in elderly are scant. Aim To evaluate efficacy and safety of secukinumab in elderly psoriasis patients over a 2﹜...
Nevertheless, the question regarding selection of the optimal medication depending on patients' characteristics and prior therapy still needs to be solved. Aim of the work To evaluate the efficacy and safety of adalimumab (ADA) as the first and subsequent biologic drug in children under 4 years ...
It is likely that with rapidly evolving scenario of biologics in psoriasis, these will prove to be very useful molecules particularly in managing severe and recalcitrant psoriasis in pediatric age group.SunilDograRahulMahajanInformaworldExpert Opinion on Drug Safety...
This phase 2b, placebo-controlled, randomized clinical trial evaluates the efficacy and safety of lebrikizumab, a novel, high-affinity, monoclonal
Lasa JS, Olivera PA, Danese S, Peyrin-Biroulet L (2022) Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis. Lancet Gastroenterol Hepatol 7(2):161–170. https://doi.org/10.1016/s2468...
The low incidence of ADA in patients limits the ability to detect any clinically significant association of ADA with safety, efficacy, or pharmacokinetics. In contrast to TCS combination therapy studies for other approved biologics (including dupilumab31 and tralokinumab32), the ADhere clinical trial...
MYL-1601D is a proposed biosimilar of originator insulin aspart, Novolog®/NovoRapid®(Ref-InsAsp-US/Ref-InsAsp-EU). Objective This study assessed the immunogenicity, efficacy, and safety of MYL-1601D with Ref-InsAsp-US in patients with type 1 diabetes mellitus (T1D). ...
Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register. Rheumatology. 2010;49(4):697-705.Saad AA, Ashcroft DM, Watson KD, Symmons DP, Noyce PR, Hyrich KL, BSRBR: Effic...
Comparison of the Efficacy and Safety of Adalimumab (Humira) and the Adalimumab Biosimilar Candidate (HS016) in Chinese Patients with Active Ankylo 热度: efficacy and safety of biologics targeting il-17 and il-23 in the treatment of moderate-to-severe plaque psoriasis a systematic review and ...