Journal of Tropical PediatricsSoliman AT, Adel A, Wagdy M, Alali M, Aziz Bedair EM. Manifestations of severe vitamin D deficiency in adolescents: Effects of intramuscular injection of a megadose of cholecalciferol. J Trop Pediatr 2011;57:303-6....
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children. Preclinical and observational data suggest that the vitamin D endocrine system has a wide spectrum of skeletal and extra-skeletal activities. There is consensus that severe vitamin D deficiency (serum 25-hydroxyv...
Severe hypercalcaemia and respiratory insufficiency associated with infantile hypophosphatasia caused by two novel mutations of the tissue-nonspecific alka... Hypercalcemia is thought to be due to impaired bone mineralization in the presence of normal bone resorption. TNALP deficiency impairs bone mineraliz...
Multivitamin supplementation decreased the risk of low birthweight (<2500 g) by 44% (0.56 [0.38-0.82] p=0.003), severe preterm birth (<34 weeks of gestation) by 39% (0.61 [0.38-0.96] p=0.03), and small size for gestational age at birth by 43% (0.57 [0.39-0.82] p=0.002). ...
and assisting with nervous system functioning. A deficiency can cause weakness, fatigue, nerve damage, andpsychosis. When the deficiency becomes severe, it causes a disease known as beriberi. There are many foods that provide thiamin so it's easy to get enough from your diet. Some of these ...
[4] This is considered a high dose of vitamin D; however, doses above this level are sometimes used for short periods of time (e.g., to reverse a severe vitamin D deficiency quickly), with safety likely determined by the dose and duration of supplementation. High-dose vitamin D ...
EFFECTS OF SEVERE MATERNAL IODINE DEFICIENCY ON THE OFFSPRING The design of the landmark trial in Papua New Guinea (15, 16) was quasi-random in that alternate families received iodine oil injections or control saline injections. The pregnancy status of women was not confirmed; it was either rec...
3.2. Thyroid Function of Pregnant Women under Different Vitamin D Statuses As shown inTable 2, women with severe vitamin D deficiency had lower FT4 levels compared with women with better vitamin status in the first trimester; women with severe vitamin D deficiency had higher TPOAb levels compared...
Likewise, in our study, the diabetic patient population was found to be higher in the group with severe vitamin D deficiency. This may be because vitamin D deficiency impairs insulin synthesis and insulin sensitivity, thus creating a predisposition to develop diabetes [31]. Compared with the ...
Vitamin A (VA) deficiency is associated with increased host susceptibility to infections, but evidence on its role in the prevention and management of viral infections is still lacking. This review aimed at summarizing the effects of VA supplementation against viral infections to support clinicians in...