We conclude that multicellular spheroids can be used to study the biological effects of fractionated radiation therapy on human brain tumor cells. Although this model cannot be used to evaluate the effect of radiation on normal tissue, it may be useful in developing more effective radiation therapy...
However, distinct cellular functions of Ras isozymes are not fully understood. Here we show the opposing roles of Ha-Ras and Ki-Ras genes in the modulation of cell sensitivity to ionizing radiation. Overexpression of active isoform of Ha-Ras (12V-Ha-Ras) in Rat2 cells increases resistance to...
became an additional obstacle to the species’ survival. Palm oil production increased 900 percent in Indonesia and Malaysia between 1980 and 2010, and, with large areas of Borneo’s tropical forests cut, the Bornean orangutan and hundreds to thousands of other species have been deprived of...
Glioblastoma is an aggressive malignant human brain tumor1. The prognosis for patients with glioblastoma is unfavorable. Despite modern treatment protocols such as surgical resection or a combination of radiation therapy and temozolomide chemotherapy, the median survival time is 15 months with only 27% ...
have received radiation treatment to your chest area in the past and have received other medicines that are similar to Opdivo have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome are pregnant or plan to become pregnant are breastfeeding or plan ...
Evidence for the harmful effects of radiation on fetal development emerges primarily from animal studies and nuclear accidents, like the Chernobyl disaster and the nuclear bombings of Hiroshima and Nagasaki. During the first 14 days post-conception, the developing embryo is at the highest risk, just...
effective in treating the cancer even as it caused fewer side effects. Overall survival at one year for the proton therapy group was 83 percent as against 81 percent for the X-ray radiation therapy group. This difference tipped slightly in favor of proton therapy but was not statistically ...
Early pubertal onset (more common after cranial radiation alone) can accelerate growth and initially mask GH insufficiency. Concerns have been raised with respect to rates of original cancer recurrence and second cancers among pediatric cancer survivors treated with GH. Studies have not supported an ...
Exposure of the large circulating blood flow through the brain could be the cause of radiation-induced lymphopenia9. Decreasing the fractions to five or less, and increasing the dose in each fraction, on the other hand, could lead to reduced lymphopenia according to simulations9. We have ...
metabolic genes in the gastrointestinal tract (GIT). We also observed an increase in protein maintenance genes, as well as in anti-apoptotic, proliferative, and pro-survival signalling. On the other hand, our results showed that exposure to low-dose radiation caused DNA damage, oxidative stress,...