Both the maternal and fetal genomes contribute to birth weight as well, as revealed in recent genome-wide association studies (GWAS)9,10, and over evolutionary time may have even conflicted on gestational duration and birth weight, as proposed in the hypothesis of the genetic conflicts of ...
We assessed whether ambient temperature and relative humidity are related to methylation on LINE-1 and Alu, as well as on genes controlling coagulation, inflammation, cortisol, DNA repair, and metabolic pathway. We examined intermediate-term associations of temperature, relative humidity, and their ...
into rats caused a slight reduction in hypothalamic concentration of epinephrine and completely prevented the accumulation of epinephrine after monoamine oxidase inhibition. The lowering of epinephrine concentration was greater with L-dopa than with D-dopa, was dose-related over a dosage range of 50 ...
The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock, which is essential for linking genetic polymorphisms to variation in phenotypes, helping fundamen
Identification of differentially methylated loci using wavelet-based functional mixed models DNA methylation is a key epigenetic modification that can modulate gene expression. Over the past decade, a lot of studies have focused on profiling DNA me... W Lee,JS Morris - 《Bioinformatics》 被引量: ...
Analysis of DNA methylation patterns of PLBs derived from Cymbidium hybridium based on MSAP The best known and most thoroughly studied epigenetic phenomenon is DNA methylation, which plays an important role in regulating gene expression during pla... X Chen,Y Ma,C Fang,... - 《Plant Cell Tis...
This appears initially as a result of a change in the methylation level of the two most abundant sensing receptors, Tsr and Tar. It is further enforced at an even higher cell density by a change in the expression level of these receptors. 展开 关键词: Escherichia coli Temperature Bacterial ...
We performed two-sample Mendelian randomisation (MR) analyses with genetic instruments for smoking behaviours and related DNA methylation in blood and summary-level GWAS data of colorectal cancer to disentangle the relationship. Colocalization analyses and prospective gene-environment interaction analyses were...
Sexual selection drives rapid phenotypic diversification of mating traits. However, we know little about the causative genes underlying divergence in sexually selected traits. Here, we investigate the genetic basis of male mating trait diversification in
Aliquots of 4 μg RNA samples were used to detect their integrity by agarose gel electrophoresis (1%). Moreover, RNA concentration and quality were examined by Nano Drop 2000/2000C spectrophotometric analysis (Thermo Fisher Scientific, Wilmington, DE, USA) at 260 and 280 nm. The ratios of ...