Physiology The effects of nicotine on the human adult visual pathway and processing THE UNIVERSITY OF ALABAMA AT BIRMINGHAM E. Eugenie Hartmann VargheseStefanie BryantNicotine, the primary addictive component found in tobacco/cigarettes, can bind to nicotinic acetylcholine receptors (nAChR), which are ...
the more of it you will need to produce the same pleasurable effect. This reaction is what drives nicotine addiction. Repeated exposure to nicotine changes the parts of your brain that help you handle stress, learn effectively and exhibit self-control. ...
Although it is more common for drug abuse to progress from tobacco to cannabis, in many cases cannabis use develops before tobacco use. Epidemiological evidence indicates that prior cannabis use increases the likelihood of becoming dependent on tobacco.
Sofuoglu, A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2015 40:2813-2821.Kevin P Jensen, Elise E DeVito, Aryeh I Herman, Gerald W Valentine, Joel Gelernter, ...
The heavy smoking risk allele might reduce the aversive effects of nicotine, but this hypothesis has not been tested in humans. We evaluated the effects of a candidate causal variant in CHRNA5, rs16969968, on the acute response to nicotine in European American (EA) and African American (AA)...
Nicotine has been found by many but not all studies to improve and mecamylamine to impair performance on cognitive tasks in humans and experimental animals. In our laboratory, a very reproducible finding has been that chronic infusion of nicotine significantly improves memory performance in a win...
There were dose-related trends toward decreased accuracy and increased response time on 3 of the 4 cognitive tests. These data do not support the hypothesis that nicotine enhances cognitive functioning in non-smokers. 展开 关键词: NICOTINE COGNITIVE PERFORMANCE SUBJECTIVE EFFECTS HUMANS NONSMOKERS ...
A large brain is a defining feature of modern humans, yet there is no consensus regarding the patterns, rates and processes involved in hominin brain size ... D Andrew,AM Zipkin,KG Hatala,... 被引量: 0发表: 2021年 Early exposure to nicotine during critical periods of brain development: ...
Menstrual or estrous cycle phase effects on the maintenance of nicotine self-administration are not particularly apparent in humans or animals, although cycle phase may influence other stages of dependence (e.g., withdrawal symptoms during cessation). Future research should evaluate further the ...
After lying in absolute rest for about 30 minutes, each subject smoked a cigarette containing 1.2 mg of nicotine. Immediately before and after smoking, blood was drawn by clear venipuncture for the evaluation of the following hemostatic variables: collagen-induced platelet aggregation by thdoi:...