Phase 1 (Go Low) lasted for the first 3 months (target <40 g net carbohydrates per day). During phase 2 (Keep it Low; months 4 through 6), net carbohydrate goal was less than 60 g (participants were instructed to choose the lowest feasible target). The goal of the 2-phased ...
The present study reports the synergistic antibacterial activity of biosynthesized silver nanoparticles (AgNPs) with the aid of a combination of chitosan and seaweed-derived polyphenols as a green synthetic route. Under optimum synthesis conditions, the
Although the goal of the present study was to examine the effects of acute consumption of sucralose when ingested in isolation, a recent report64 demonstrated that short-term daily consumption of sucralose with, but not without, carbohydrates was associated with impairments in insulin sensitivity, ...
The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) is a complex ecosystem that drives tumor progression; however, in-depth single cell characterization of the PDAC TME and its role in response to therapy is lacking. Here, we perform single-cell RNA sequencing on freshly ...
Cellular metabolism encompasses a complex array of biochemical reactions that utilize specific nutrients, including carbohydrates, fatty acids, and amino acids. These nutrients are the primary sources for maintaining energy homeostasis and synthesizing macromolecules.25Our focus here is on cancer metabolism,...
You know lack of sleep can make you grumpy and foggy. You may not know what it can do to your sex life, memory, health, looks, and ability to lose weight. Here are 10 surprising -- and serious -- effects of sleep loss.
Another nutritionist assessed, calculated and inputted the quantities and energy supply of the three major nutrients (carbohydrates, protein and fat) based on the types and quantities of foods consumed by the participants as shown in Supplemental Table 3. Participants who have not complied with the...
Insulin has been in therapeutic use for around 70 years, and the range of adverse effects associated with its use is very limited. Insulin allergy and othe
Participants came to the clinic at 0800 hours in fasting condition and had a breakfast corresponding to 521 kcal and 100 g carbohydrates, of which 38 g were disaccharides (26 sucrose) and 20.5 g monosaccharides. Blood samples were drawn in two separate tubes, one with Trasylol (...
RER is dependent on energy substrate utilization, ranging from above 1 to 0.7, which indicates preferential use of carbohydrates and lipids, respectively. Locomotor activity was measured on X, Y and Z axes using infrared beams. Energy expenditure was calculated using VO2 and RER values and ...