This chapter evaluates the efficiency of alpha interferon (IFN-α) alone or combined with lamivudine in the treatment of children with hepatitis B, especially those with post-transfusional chronic hepatitis. Infection with hepatitis B virus (HBV) is considered a major health problem worldwide, with...
Objective IFN-β is believed to have immunomodulatory properties which might have a beneficial effect in rheumatoid arthritis (RA) by inhibition of TNF-α and enhancement of IL-10 and IL-1RA production, as has been shown in vitro . The aim of this study was to evaluate the effect of IFN-...
Abstract Objective Interferon‐β (IFNβ) treatment is emerging as a potentially effective form of therapy in various immune‐mediated conditions. This study evaluated the effects of IFNβ therapy on the cell infiltrate, cytokine profile, and expression of metalloproteinase 1 (MMP‐1) in synovial ti...
Aim: Interferon-α (IFN-α) has been extensively explored for its efficacy in various disease conditions and is currently used as a standard treatment in several of these. Its use is accompanied by a wide variety of possible side effects. These side-effects may hamper reaching and maintaining ...
of the therapeutic process,12there is currently no solid evidence showing that any nutrition-related regimen can be a primary treatment for cancer.13However, preclinical studies suggest that calorie and energy restrictions can hinder tumor growth and progression and increase the efficacy of chemotherapy...
In WPMY-1 cells, Tan IIA treatment arrested the cell cycle at the G2/M phase and downregulated the expression of CCNB1. However, in RWPE-1 cells, Tan IIA treatment arrested cell cycle at the G0/G1 phase and reduced the expression of CCND1. Tan IIA also reduced the expression of ER...
In addition, patients should avoid other hepatotoxic agents, including anesthetics, statins, and large quantities of alcohol, during interferon treatment. Acetaminophen should be used judiciously, and patients should be cautioned regarding the risks of exceeding recommended dosages. Interferon side effects...
SummaryTo evaluate the effect and side-effects of alpha interferon 2B (IFN) treatment in haemophilia patients with chronic hepatitis C (positive HCV antibody test, positive HCV-RNA test and ALT levels >2.5 × upper limit of normal) eight HIV and HBs-ag negative haemophilia patients were treated...
Interferon alpha therapy in essential thrombocythemia and polycythemia vera—a systematic review and meta-analysis Article 01 September 2020 Efficacy and tolerability of granulocyte colony-stimulating factors in cancer patients after chemotherapy: A systematic review and Bayesian network meta-analysis Ar...
Since the hyper-IgE syndrome is known to improve under alpha-interferon (alpha-IFN) therapy, we treated 7 patients with severe AE and high serum IgE exclusively with 3 x 10(6) units IFN alpha 2b thrice weekly for 3 months. Before treatment the skin infiltrates mainly consisted of CD3+/...