Reviews in Endocrine & Metabolic DisordersSkov J. Effects of GLP-1 in the kidney. Rev Endocr Metab Disord 2014; 15: 197-207Skov J. Effects of GLP-1 in the kidney. Rev Endocr Metab Disord. 2014;15(3):197-207.Skov J. Effects of GLP-1 in the kidney. Rev Endocr Metab Disord 2014;...
with the development of acute kidney injury.The present review aims to present the available data regarding the effects of GLP-1 receptor agonists on renal function,their use in subjects with chronic renal failure and their possible association with acute kidney injury.Based on the current evidence...
There have been various in vitro studies over the last ten years that have studied the anti-inflammatory effects of GLP-1 receptor (GLP-1R) agonists, focusing on macrophage cell lines. One such study by Lu and colleagues in RAW264.7 macrophages demonstrated increased pro-inflammatory cytokine ...
GLP-1 receptor agonistsDiabetic kidney diseaseAlbuminuriaBlood pressureIncretin-based therapiesGlucagon-like peptide (GLP)-1 receptor agonists are the cornerstone in the treatment of hyperglycemia in many people suffering from type 2 diabetes (T2D). These drugs have potent glucose-lowering actions and, ...
It contains the same active ingredient as found in Ozempic, which is approved to help control blood sugar in patients with type 2 diabetes, for cardiovascular risk reduction in patients with heart disease, and to reduce the risk of serious kidney problems in adults with type 2 diabetes (T2D)...
Further studies are needed to assess the potential cardiovascular and renal benefits of combination therapy and to determine suitable patient population for the therapy. Graphical abstract Suspected clinical impacts of GLP-1RAs, SGLT2is, and finerenone oncardiovascular and kidney outcomes. CV, ...
A common consequence ofDMis kidney complications, which could lead to kidney failure. We studied the potential effects of treatment with insulin and the glucagon‐like peptide 1 receptor (GLP‐1R) agonist liraglutide on the diabetic kidney proteome through the use of the db/db mouse model system...
Kidney problems(kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems to get worse. Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use TRULICITY....
Further studies are needed to assess the potential cardiovascular and renal benefits of combination therapy and to determine suitable patient population for the therapy. Graphical abstract Suspected clinical impacts of GLP-1RAs, SGLT2is, and finerenone oncardiovascular and kidney outcomes. CV, ...
In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems to get worse.Gallbladder problems. Gallbladder problems including gall stones have happened in some people who take liraglutide. Tell your healthcare provider...