FECD is more common in women than men, but the basis for this observation is poorly understood. To understand the sex disparity in FECD prevalence, we studied the effects of the sex hormone 17-尾 estradiol (E2) on growth, oxidative stress, and metabolism in primary cultures of HCEnCs ...
The sodium salt of 17-estradiol 3-sulfate is a minor component (2.5-9.5%) of several widely marketed estrogen hormone replacement products, such as Premarin庐, that are approved by the U.S. Food and Drug Administration and have been prescribed and studied in women and men for more than 65...
Blood samples were analyzed for testosterone, androstenedione, and estradiol levels. The researchers found a significant difference between pre- (4.36 ± 56 ng/mL) and post- (5.51 ± 0.35 ng/mL) testosterone levels, as well as pre- (0.88 ± 0.20) and post- (7.46...
People have always considered the exposure to non-ionising radiation with scepticism. The prospect that exposure to electromagnetic fields (EMF) can have a deleterious effect or any effect on cellular behaviour has been debated in scientific and journali
Estradiol is a drug prescribed to treat the symptoms of menopause and prevent bone fractures (osteoporosis), painful uterine bleeding, vaginal pain, dryness, and atrophy associated with menopause. Estradiol is also prescribed for the treatment of breast
The effect of estradiol-17尾 (E2) and progesterone (P) on the structure of myofilaments of the smooth muscle of the myometrium of cats was studied by electron microscopy. Animals which had been ovariectomized for at least four weeks were divided into three treatment groups. Group I received ...
The prevalence of delayed menopause was slightly increased in cadmium polluted areas compared with that in the control area. Cadmium may mimic the effects of estradiol in delaying the occurrence of menopause. There are several limitations in our study. First, we could not obtain the internal dose...
Common(1% to 10%): Increased estradiol, hypogonadism Uncommon(0.1% to 1%): Increased blood testosterone Frequency not reported: Signs of virilization in women (e.g., hoarseness, acne, hirsutism, menstrual irregularity, clitoral enlargement, and alopecia), precocious puberty (in prepubertal males)...
Effects of exogenous oxytocin and estradiol on resting-state functional connectivity in women and men Marie Coenjaerts Berina Adrovic Dirk Scheele Scientific Reports (2023) Does Testosterone Modulate Aggression and Mating Behavior in Humans? A Narrative Review of Two Decades of single-dose Testosteron...
In women, agonistic as well as antagonistic effects of estrogens and progestins need to be taken into account. In fact, estradiol may modulate testosterone effects on haemostasis. Androgen medication in premenopausal women, such as danazol, was found to reduce PAI 1 suggesting an improvement of ...