Effects of delta9adjustment of factorsadjusted orthogonalityfactorial experimentnonorthogonal designpairwise orthogonalityBloom AS, Haavik CO, Strehlow D.doi:10.1016/0024-3205(78)90400-9A BloomHAAVIK, COSTREHLOW, DLife SciLife Sciences
The effects of psychotropic drugs on THC-induced long-lasting muricide were investigated in rats. Changes in open field activity (ambulation and rearing) of the rat were concurrently assessed as an index of behavioral toxicity. Imipramine-like antidepressants, atropine, and antiparkinsonism drugs exhib...
To estimate the effect of the water-layer thickness on the temperature drop, we used three values for \({\Delta x}_{{{\rm{H}}}_2{{\rm{O}}}\), a minimal value of 25 nm slightly larger than the diameter of the ribosome and two values of 100 nm and 200 nm which capture...
Targeting cannabinoid receptor type 1 (CB1R) has shown promise for treating opioid withdrawal symptoms. This study aimed to investigate the efficacy of a s
Effects of chronic delta-8-THC and delta-9-THC administration in the rat Rats chronically treated with increasing daily doses of delta 9-tetrahydrocannabinol (delta 9-THC) for up to 5 or 10 days exhibit a withdrawal-like behavioural response when challenged with clomipramine, a potent inhibitor...
$${\chi }_{i}=\frac{\#\{j,k\}|{\delta }_{j,k}={\delta }_{i,j}={\delta }_{i,k}=1}{nv(v-1)}$$ (12) that is, the number of triadic closures around agent i in proportion to all possible such triads. Using this definition, let χ denote the average local clustering...
Opioid Antagonism of Cannabinoid Effects: Differences between Marijuana Smokers and Nonmarijuana Smokers In non-human animals, opioid antagonists block the reinforcing and discriminative-stimulus effects of Delta(9)-tetrahydrocannabinol (THC), while in human m... Haney,Margaret - 《Neuropsychopharmacology ...
The cannabis plant contains more than 100 different chemicals called cannabinoids. Each one has a different effect on the body.Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)are the main chemicals used in medicine. THC also produces the “high” people feel when they smoke marijuana or ...
Assuming that the median time to sustained improvement or resolution was 12 days in control group and 9 days in LHQW group, 652 patients would be randomized to LHQW or placebo group (1:1) with a 95% power with a two-sided significance of 0.05 according to PASS software. In practice, ...
In the present study we have investigated the long-term effects of administering increasing doses of delta-9-tetrahydrocannabinol [THC; 2.5, 5, 10 mg/kg; i.p.] from postnatal day (pnd) 28 to 45, alone and/or in conjunction with 3,4-methylenedioxymethamphetamine [MDMA; two daily doses ...