Effects of delta9adjustment of factorsadjusted orthogonalityfactorial experimentnonorthogonal designpairwise orthogonalityBloom AS, Haavik CO, Strehlow D.doi:10.1016/0024-3205(78)90400-9A BloomHAAVIK, COSTREHLOW, DLife SciLife Sciences
The effects of psychotropic drugs on THC-induced long-lasting muricide were investigated in rats. Changes in open field activity (ambulation and rearing) of the rat were concurrently assessed as an index of behavioral toxicity. Imipramine-like antidepressants, atropine, and antiparkinsonism drugs exhib...
To estimate the effect of the water-layer thickness on the temperature drop, we used three values for \({\Delta x}_{{{\rm{H}}}_2{{\rm{O}}}\), a minimal value of 25 nm slightly larger than the diameter of the ribosome and two values of 100 nm and 200 nm which capture...
Targeting cannabinoid receptor type 1 (CB1R) has shown promise for treating opioid withdrawal symptoms. This study aimed to investigate the efficacy of a s
Effects of chronic delta-8-THC and delta-9-THC administration in the rat Rats chronically treated with increasing daily doses of delta 9-tetrahydrocannabinol (delta 9-THC) for up to 5 or 10 days exhibit a withdrawal-like behavioural response when challenged with clomipramine, a potent inhibitor...
Assuming that the median time to sustained improvement or resolution was 12 days in control group and 9 days in LHQW group, 652 patients would be randomized to LHQW or placebo group (1:1) with a 95% power with a two-sided significance of 0.05 according to PASS software. In practice, ...
The vorticity effect on solitary wave profiles has not been solved experimentally; previous studies theoretically and numerically showed that when a solitary wave progressed in the positive direction, the effective wavelength of a solitary wave with posi
Opioid Antagonism of Cannabinoid Effects: Differences between Marijuana Smokers and Nonmarijuana Smokers In non-human animals, opioid antagonists block the reinforcing and discriminative-stimulus effects of Delta(9)-tetrahydrocannabinol (THC), while in human m... Haney,Margaret - 《Neuropsychopharmacology ...
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In the present study we have investigated the long-term effects of administering increasing doses of delta-9-tetrahydrocannabinol [THC; 2.5, 5, 10 mg/kg; i.p.] from postnatal day (pnd) 28 to 45, alone and/or in conjunction with 3,4-methylenedioxymethamphetamine [MDMA; two daily doses ...