Exposure to asbestos dust may stimulate a severe reaction in the lungs leading to parechymal and pleural fibrosis. There is also an association between exposure to asbestos and the development of bronchogenic carcinomas and mesotheliomas. While the pathogenesis of these disorders is unknown, altered...
Asbestosis Prognosisdepends on the extent and duration of asbestos exposure, in addition to numerous individual health factors. According to the Mayo Clinic, asbestosis can lead to: High blood pressure in the lungs (pulmonary hypertension)
We have demonstrated that C57BL/6–129 hybrid mice with genes for both the 55kd and 75kd receptors for TNF-α knocked out (TNF-αRKO) fail to develop fibroproliferative lesions after asbestos exposure. There is good evidence that TNF-α plays a major role in mediating interstitial pulmonary...
Ultrafine particles (PM0.1), which are present in the air in large numbers, pose a health risk. They generally enter the body through the lungs but translocate to essentially all organs. Compared to fine particles (PM2.5), they cause more pulmonary infla
The initial dose of Actiq to treat episodes of breakthrough cancer pain is always 200 mcg. The Actiq unit should be consumed over 15 minutes. The dose may be increased under a physician's supervision until pain relief is achieved. What Drugs, Substances, or Supplements Interact with Actiq?
The following adverse reactions have been identified during post-approval use of ARRANON. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. ...
Exposure to ambient airborne particulate matter is a major risk factor for mortality and morbidity, associated with asthma, lung cancer, heart disease, myocardial infarction, and stroke, and more recently type 2 diabetes, dementia and loss of cognitive f
We have demonstrated that C57BL/6–129 hybrid mice with genes for both the 55kd and 75kd receptors for TNF-α knocked out (TNF-αRKO) fail to develop fibroproliferative lesions after asbestos exposure. There is good evidence that TNF-α plays a major role in mediating interstitial pulmonary...
Exposure to ambient air pollution is a serious and common public health concern associated with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air pollution on the pulmonary and cardiovascular systems have been well established in a series of major epidemiologic...
Herein, we have investigated the toxicity of SWCNTs and MWCNTs in vitro and in vivo, and assessed their therapeutic effects on a typical animal model of breast cancer in order to obtain: first, the cytotoxicity effects of CNTs on MC4L2 cell and mice, sec