This "effector triggered immunity" (ETI) was first discovered in plants but recent evidence suggest that the process is also well conserved in metazoans. We will discuss salient points of the mechanism of ETI in metazoans from recent studies done in mammalian cells and invertebrate model hosts. ...
Pattern-triggered immunity (PTI). The immune response elicited after the ligation of a PRR by its microbial ligand. A more appropriate term would in fact be MAMP-triggered immunity, for the reasons described above. Resistance gene (R gene). The original plant terminology for a host gene encodi...
Such 'effector-triggered immunity' was previously demonstrated mainly in plants, but recent data confirm that animals can also use this strategy. 展开 关键词: PORE-FORMING TOXINS DAMAGE-RESPONSE FRAMEWORK BACTERIAL EFFECTORS INNATE IMMUNITY TRANSLATIONAL INHIBITION MICROBIAL PATHOGENESIS LEGIONELLA-PNEUMOPHILA...
This type of immune surveillance system has been demonstrated in plants and termed "effector-triggered immunity" (ETI) [2]. Recently, the concept of ETI has been extended to metazoans and proof of its importance as an innate immune mechanism has now been provided in Drosophila melanogaster, ...
Our data indicate that one function of a subset of TCP proteins is to regulate defense gene expression in antagonism to SRFR1, and suggest a mechanism for an intimate connection between plant development and immunity. 展开 关键词: Arabidopsis thaliana Pseudomonas syringae effector-triggered immunity ...
Here, we report that CPR5, which plays a key inhibitory role in effector-triggered immunity (ETI) and programmed cell death (PCD) in plants, is a novel transmembrane nucleoporin. CPR5 associates with anchors of the NPC selective barrier to constrain nuclear access of signaling cargos and ...
Effector-triggered immunity (ETI), the major host defense mechanism in plants, is often associated with programmed cell death (PCD). Plants lack close homologs of caspases, the key mediators of PCD in animals. So although the NB-LRR receptors involved in ETI are well studied, how they activat...
Plants have two related immune systems to defend themselves against pathogen attack. Initially, pattern-triggered immunity is activated upon recognition of microbe-associated molecular patterns by pattern recognition receptors. Pathogenic bacteria delive
Pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) in plants enable them to respond to pathogens by activating the production of defence metabolites that orchestrate immune responses1,2,3,4. How the production of defence metabolites is promoted by immune receptors and coordinated ...
Genotype-specific incompatibility in legume–rhizobium symbiosis has been suggested to be controlled by effector-triggered immunity underlying pathogenic host-bacteria interactions. However, the rhizobial determinant interacting with the host resistance